Varaico: Literature-Extracted Genetic Variants

Gene:CFTR
Variant:p.T338S
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CFTR

NM_000492.4:p.T338S

Associated Papers

Contribution of a leucine residue in the first transmembrane segment to the selectivity filter region in the CFTR chloride channel.

Negoda A et al.

Biochimica Et Biophysica Acta. Biomembranes, 2017

Architecture and functional properties of the CFTR channel pore.

Linsdell P

Cellular and Molecular Life Sciences : Cmls, 2017

Functional architecture of the CFTR chloride channel.

Linsdell P

Molecular Membrane Biology, 2014

CFTR: what's it like inside the pore?

Liu X et al.

Journal of Experimental Zoology. Part A, Comparative Experimental Biology, 2003

Relationship between anion binding and anion permeability revealed by mutagenesis within the cystic fibrosis transmembrane conductance regulator chloride channel pore.

Linsdell P

The Journal of Physiology, 2001

Non-pore lining amino acid side chains influence anion selectivity of the human CFTR Cl- channel expressed in mammalian cell lines.

Linsdell P et al.

The Journal of Physiology, 1998

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."