Associated Papers
Molecular dynamics study of Cl- permeation through cystic fibrosis transmembrane conductance regulator (CFTR).
Zeng ZW et al.
Cellular and Molecular Life Sciences : Cmls, 2023
On the relationship between anion binding and chloride conductance in the CFTR anion channel.
Linsdell P
Biochimica Et Biophysica Acta. Biomembranes, 2021
Contribution of the eighth transmembrane segment to the function of the CFTR chloride channel pore.
Negoda A et al.
Cellular and Molecular Life Sciences : Cmls, 2019
Architecture and functional properties of the CFTR channel pore.
Linsdell P
Cellular and Molecular Life Sciences : Cmls, 2017
The pore architecture of the cystic fibrosis transmembrane conductance regulator channel revealed by co-mutation in pore-forming transmembrane regions.
Qian F et al.
Physiological Research, 2016
CFTR Controls the Activity of NF-κB by Enhancing the Degradation of TRADD.
Wang H et al.
Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology, 2016
Stoichiometry and novel gating mechanism within the cystic fibrosis transmembrane conductance regulator channel.
Qian F et al.
Experimental Physiology, 2014
Functional architecture of the CFTR chloride channel.
Linsdell P
Molecular Membrane Biology, 2014
Transcomplementation by a truncation mutant of cystic fibrosis transmembrane conductance regulator (CFTR) enhances ΔF508 processing through a biomolecular interaction.
Cebotaru L et al.
The Journal of Biological Chemistry, 2013
Differential contribution of TM6 and TM12 to the pore of CFTR identified by three sulfonylurea-based blockers.
Cui G et al.
Pflugers Archiv : European Journal of Physiology, 2012
Regulation of conductance by the number of fixed positive charges in the intracellular vestibule of the CFTR chloride channel pore.
Zhou JJ et al.
The Journal of General Physiology, 2010
Evidence for direct CFTR inhibition by CFTR(inh)-172 based on Arg347 mutagenesis.
Caci E et al.
The Biochemical Journal, 2008
Insight in eukaryotic ABC transporter function by mutation analysis.
Frelet A et al.
Febs Letters, 2006
Mutation-induced blocker permeability and multiion block of the CFTR chloride channel pore.
Gong X et al.
The Journal of General Physiology, 2003
Mechanism of lonidamine inhibition of the CFTR chloride channel.
Gong X et al.
British Journal of Pharmacology, 2002
CFTR is a monomer: biochemical and functional evidence.
Chen JH et al.
The Journal of Membrane Biology, 2002
Molecular determinants of Au(CN)(2)(-) binding and permeability within the cystic fibrosis transmembrane conductance regulator Cl(-) channel pore.
Gong X et al.
The Journal of Physiology, 2002
Asymmetric structure of the cystic fibrosis transmembrane conductance regulator chloride channel pore suggested by mutagenesis of the twelfth transmembrane region.
Gupta J et al.
Biochemistry, 2001
Perturbation of the pore of the cystic fibrosis transmembrane conductance regulator (CFTR) inhibits its atpase activity.
Kogan I et al.
The Journal of Biological Chemistry, 2001
Interaction between permeation and gating in a putative pore domain mutant in the cystic fibrosis transmembrane conductance regulator.
Zhang ZR et al.
Biophysical Journal, 2000
Direct comparison of NPPB and DPC as probes of CFTR expressed in Xenopus oocytes.
Zhang ZR et al.
The Journal of Membrane Biology, 2000
Structural and ionic determinants of 5-nitro-2-(3-phenylprophyl-amino)-benzoic acid block of the CFTR chloride channel.
Walsh KB et al.
British Journal of Pharmacology, 1999
Control of CFTR channel gating by phosphorylation and nucleotide hydrolysis.
Gadsby DC et al.
Physiological Reviews, 1999
Pharmacology of CFTR chloride channel activity.
Schultz BD et al.
Physiological Reviews, 1999
Identification of cystic fibrosis transmembrane conductance regulator channel-lining residues in and flanking the M6 membrane-spanning segment.
Cheung M et al.
Biophysical Journal, 1996
Novel pore-lining residues in CFTR that govern permeation and open-channel block.
McDonough S et al.
Neuron, 1994
Extent of the selectivity filter conferred by the sixth transmembrane region in the CFTR chloride channel pore.
Gupta J et al.
Molecular Membrane Biology, 0