Associated Papers
Changes in the R-region interactions depend on phosphorylation and contribute to PKA and PKC regulation of the cystic fibrosis transmembrane conductance regulator chloride channel.
Poroca DR et al.
Faseb Bioadvances, 2020
Role of tyrosine phosphorylation in the muscarinic activation of the cystic fibrosis transmembrane conductance regulator (CFTR).
Billet A et al.
The Journal of Biological Chemistry, 2013
AMP-activated protein kinase phosphorylation of the R domain inhibits PKA stimulation of CFTR.
King JD et al.
American Journal of Physiology. Cell Physiology, 2009
Cystic fibrosis transmembrane conductance regulator: a chloride channel gated by ATP binding and hydrolysis.
Bompadre SG et al.
Sheng Li Xue Bao : [acta Physiologica Sinica], 2007
Capsaicin potentiates wild-type and mutant cystic fibrosis transmembrane conductance regulator chloride-channel currents.
Ai T et al.
Molecular Pharmacology, 2004
Stimulatory and inhibitory protein kinase C consensus sequences regulate the cystic fibrosis transmembrane conductance regulator.
Chappe V et al.
Proceedings of the National Academy of Sciences of the United States of America, 2004
Phosphorylation of protein kinase C sites in NBD1 and the R domain control CFTR channel activation by PKA.
Chappe V et al.
The Journal of Physiology, 2003
PKC-mediated stimulation of amphibian CFTR depends on a single phosphorylation consensus site. insertion of this site confers PKC sensitivity to human CFTR.
Button B et al.
The Journal of General Physiology, 2001
Control of CFTR channel gating by phosphorylation and nucleotide hydrolysis.
Gadsby DC et al.
Physiological Reviews, 1999
Regulation of the cystic fibrosis transmembrane conductance regulator Cl- channel by negative charge in the R domain.
Berger HA et al.
The Japanese Journal of Physiology, 1994
Regulation of the cystic fibrosis transmembrane conductance regulator Cl- channel by negative charge in the R domain.
Rich DP et al.
The Journal of Biological Chemistry, 1993
Protein kinase A (PKA) still activates CFTR chloride channel after mutagenesis of all 10 PKA consensus phosphorylation sites.
Chang XB et al.
The Journal of Biological Chemistry, 1993
Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel.
Cheng SH et al.
Cell, 1991
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