Varaico: Literature-Extracted Genetic Variants

Gene:CFTR
Variant:p.T788A
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CFTR

NM_000492.4:p.T788A

Associated Papers

Role of tyrosine phosphorylation in the muscarinic activation of the cystic fibrosis transmembrane conductance regulator (CFTR).

Billet A et al.

The Journal of Biological Chemistry, 2013

AMP-activated protein kinase phosphorylation of the R domain inhibits PKA stimulation of CFTR.

King JD et al.

American Journal of Physiology. Cell Physiology, 2009

Protein kinase A (PKA) still activates CFTR chloride channel after mutagenesis of all 10 PKA consensus phosphorylation sites.

Chang XB et al.

The Journal of Biological Chemistry, 1993

Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel.

Cheng SH et al.

Cell, 1991

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."