Associated Papers
Protein kinase A phosphorylation potentiates cystic fibrosis transmembrane conductance regulator gating by relieving autoinhibition on the stimulatory C terminus of the regulatory domain.
Chen JH
The Journal of Biological Chemistry, 2020
Molecular Basis for Fe(III)-Independent Curcumin Potentiation of Cystic Fibrosis Transmembrane Conductance Regulator Activity.
Wang G
Biochemistry, 2015
Role of tyrosine phosphorylation in the muscarinic activation of the cystic fibrosis transmembrane conductance regulator (CFTR).
Billet A et al.
The Journal of Biological Chemistry, 2013
AMP-activated protein kinase phosphorylation of the R domain inhibits PKA stimulation of CFTR.
King JD et al.
American Journal of Physiology. Cell Physiology, 2009
Cystic fibrosis transmembrane conductance regulator: a chloride channel gated by ATP binding and hydrolysis.
Bompadre SG et al.
Sheng Li Xue Bao : [acta Physiologica Sinica], 2007
Capsaicin potentiates wild-type and mutant cystic fibrosis transmembrane conductance regulator chloride-channel currents.
Ai T et al.
Molecular Pharmacology, 2004
Protein kinase A regulates ATP hydrolysis and dimerization by a CFTR (cystic fibrosis transmembrane conductance regulator) domain.
Howell LD et al.
The Biochemical Journal, 2004
Contribution of R domain phosphoserines to the function of CFTR studied in Fischer rat thyroid epithelia.
Baldursson O et al.
American Journal of Physiology. Lung Cellular and Molecular Physiology, 2000
Structure and function of the CFTR chloride channel.
Sheppard DN et al.
Physiological Reviews, 1999
Stimulation of CFTR activity by its phosphorylated R domain.
Winter MC et al.
Nature, 1997
CFTR activation: additive effects of stimulatory and inhibitory phosphorylation sites in the R domain.
Wilkinson DJ et al.
The American Journal of Physiology, 1997
Regulation of the cystic fibrosis transmembrane conductance regulator Cl- channel by negative charge in the R domain.
Berger HA et al.
The Japanese Journal of Physiology, 1994
Regulation of the cystic fibrosis transmembrane conductance regulator Cl- channel by negative charge in the R domain.
Rich DP et al.
The Journal of Biological Chemistry, 1993
Protein kinase A (PKA) still activates CFTR chloride channel after mutagenesis of all 10 PKA consensus phosphorylation sites.
Chang XB et al.
The Journal of Biological Chemistry, 1993
Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel.
Cheng SH et al.
Cell, 1991