Associated Papers
Cystic fibrosis risk variants confer protection against inflammatory bowel disease.
Yu M et al.
Cell Genomics, 2025
Cystic fibrosis risk variants confer protection against inflammatory bowel disease.
Yu M et al.
Medrxiv : the Preprint Server for Health Sciences, 2024
Benchmarking AlphaMissense Pathogenicity Predictions Against Cystic Fibrosis Variants.
McDonald EF et al.
Biorxiv : the Preprint Server for Biology, 2024
Benchmarking AlphaMissense pathogenicity predictions against cystic fibrosis variants.
McDonald EF et al.
Plos One, 2024
C FTR variants are associated with chronic bronchitis in smokers.
Saferali A et al.
The European Respiratory Journal, 2022
Contribution of the eighth transmembrane segment to the function of the CFTR chloride channel pore.
Negoda A et al.
Cellular and Molecular Life Sciences : Cmls, 2019
Structural mechanisms of CFTR function and dysfunction.
Hwang TC et al.
The Journal of General Physiology, 2018
Mutations in SELENBP1, encoding a novel human methanethiol oxidase, cause extraoral halitosis.
Pol A et al.
Nature Genetics, 2018
Contribution of a leucine residue in the first transmembrane segment to the selectivity filter region in the CFTR chloride channel.
Negoda A et al.
Biochimica Et Biophysica Acta. Biomembranes, 2017
External Zn(2+) binding to cysteine-substituted cystic fibrosis transmembrane conductance regulator constructs regulates channel gating and curcumin potentiation.
Wang G et al.
The Febs Journal, 2016
Conformational changes opening and closing the CFTR chloride channel: insights from cysteine scanning mutagenesis.
El Hiani Y et al.
Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire, 2014
Relative contribution of different transmembrane segments to the CFTR chloride channel pore.
Wang W et al.
Pflugers Archiv : European Journal of Physiology, 2014
Functional architecture of the CFTR chloride channel.
Linsdell P
Molecular Membrane Biology, 2014
Relative movements of transmembrane regions at the outer mouth of the cystic fibrosis transmembrane conductance regulator channel pore during channel gating.
Wang W et al.
The Journal of Biological Chemistry, 2012
Do common in silico tools predict the clinical consequences of amino-acid substitutions in the CFTR gene?
Dorfman R et al.
Clinical Genetics, 2010
Novel residues lining the CFTR chloride channel pore identified by functional modification of introduced cysteines.
Fatehi M et al.
The Journal of Membrane Biology, 2009