Associated Papers
Two positively charged amino acid side-chains in the inner vestibule of the CFTR channel pore play analogous roles in controlling anion binding and anion conductance.
Linsdell P et al.
Cellular and Molecular Life Sciences : Cmls, 2021
Conformational change of the extracellular parts of the CFTR protein during channel gating.
Negoda A et al.
Cellular and Molecular Life Sciences : Cmls, 2018
Structural mechanisms of CFTR function and dysfunction.
Hwang TC et al.
The Journal of General Physiology, 2018
Transmembrane helical interactions in the CFTR channel pore.
Das J et al.
Plos Computational Biology, 2017
Conformational changes opening and closing the CFTR chloride channel: insights from cysteine scanning mutagenesis.
El Hiani Y et al.
Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire, 2014
Metal bridges illuminate transmembrane domain movements during gating of the cystic fibrosis transmembrane conductance regulator chloride channel.
El Hiani Y et al.
The Journal of Biological Chemistry, 2014
Functional architecture of the CFTR chloride channel.
Linsdell P
Molecular Membrane Biology, 2014
Structural basis for the channel function of a degraded ABC transporter, CFTR (ABCC7).
Bai Y et al.
The Journal of General Physiology, 2011
Functional arrangement of the 12th transmembrane region in the CFTR chloride channel pore based on functional investigation of a cysteine-less CFTR variant.
Qian F et al.
Pflugers Archiv : European Journal of Physiology, 2011
Alignment of transmembrane regions in the cystic fibrosis transmembrane conductance regulator chloride channel pore.
Wang W et al.
The Journal of General Physiology, 2011
Regulation of conductance by the number of fixed positive charges in the intracellular vestibule of the CFTR chloride channel pore.
Zhou JJ et al.
The Journal of General Physiology, 2010
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