Associated Papers
Synergistic Potentiation of Cystic Fibrosis Transmembrane Conductance Regulator Gating by Two Chemically Distinct Potentiators, Ivacaftor (VX-770) and 5-Nitro-2-(3-Phenylpropylamino) Benzoate.
Lin WY et al.
Molecular Pharmacology, 2016
A single amino acid substitution in CFTR converts ATP to an inhibitory ligand.
Lin WY et al.
The Journal of General Physiology, 2014
A stable ATP binding to the nucleotide binding domain is important for reliable gating cycle in an ABC transporter CFTR.
Shimizu H et al.
The Journal of Physiological Sciences : Jps, 2010
The two ATP binding sites of cystic fibrosis transmembrane conductance regulator (CFTR) play distinct roles in gating kinetics and energetics.
Zhou Z et al.
The Journal of General Physiology, 2006
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