Associated Papers
Structural basis for CFTR inhibition by CFTRinh-172.
Young PG et al.
Proceedings of the National Academy of Sciences of the United States of America, 2024
CFTR function, pathology and pharmacology at single-molecule resolution.
Levring J et al.
Nature, 2023
Cystic fibrosis transmembrane conductance regulator: using differential reactivity toward channel-permeant and channel-impermeant thiol-reactive probes to test a molecular model for the pore.
Alexander C et al.
Biochemistry, 2009
CFTR: Ligand exchange between a permeant anion ([Au(CN)2]-) and an engineered cysteine (T338C) blocks the pore.
Serrano JR et al.
Biophysical Journal, 2006
Insight in eukaryotic ABC transporter function by mutation analysis.
Frelet A et al.
Febs Letters, 2006
The DeltaF508 mutation disrupts packing of the transmembrane segments of the cystic fibrosis transmembrane conductance regulator.
Chen EY et al.
The Journal of Biological Chemistry, 2004
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