Varaico: Literature-Extracted Genetic Variants

Gene:CGAS
Variant:p.D319A
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CGAS

NM_138441.3:p.D319A

Associated Papers

Activation of the cGAS-STING-IRF3 Axis by Type I and II Interferons Contributes to Host Defense.

Tong Z et al.

Advanced Science (weinheim, Baden-wurttemberg, Germany), 2024

Nuclear cGAS restricts L1 retrotransposition by promoting TRIM41-mediated ORF2p ubiquitination and degradation.

Zhen Z et al.

Nature Communications, 2023

The STING phase-separator suppresses innate immune signalling.

Yu X et al.

Nature Cell Biology, 2021

Mn2+ Directly Activates cGAS and Structural Analysis Suggests Mn2+ Induces a Noncanonical Catalytic Synthesis of 2'3'-cGAMP.

Zhao Z et al.

Cell Reports, 2020

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."