Varaico: Literature-Extracted Genetic Variants

Gene:CGAS
Variant:p.K63R
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CGAS

NM_138441.3:p.K63R

Associated Papers

PKCλ/ι inhibition activates an ULK2-mediated interferon response to repress tumorigenesis.

Linares JF et al.

Molecular Cell, 2021

USP29 maintains the stability of cGAS and promotes cellular antiviral responses and autoimmunity.

Zhang Q et al.

Cell Research, 2020

32457395 (PubMed )
Supplement: 41422_2020_341_MOESM5_ESM.pdf

The E3 ubiquitin ligase RNF185 facilitates the cGAS-mediated innate immune response.

Wang Q et al.

Plos Pathogens, 2017

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."