Associated Papers
WES-Based Screening of a Swedish Patient Series with Parkinson's Disease.
Kafantari E et al.
Genes, 2025
The Aggregation Continuum of α-Synuclein and Its Relevance to Brain Aging.
Rana A et al.
Acs Chemical Neuroscience, 2025
Effects of pathological mutations on the CHCHD2 monomer structure: A study by AlphaFold3 linked to the generation of conformational ensembles.
Özmen ZA et al.
Computers in Biology and Medicine, 2025
Dysregulation of mitochondrial α-ketoglutarate dehydrogenase leads to elevated lipid peroxidation in CHCHD2-linked Parkinson's disease models.
Gao G et al.
Nature Communications, 2025
Role of the mitochondrial regulatory factor CHCHD2 in neurodegenerative diseases.
Guo X et al.
Frontiers in Neuroscience, 2025
Loss of CHCHD2 Stability Coordinates with C1QBP/CHCHD2/CHCHD10 Complex Impairment to Mediate PD-Linked Mitochondrial Dysfunction.
Ren YL et al.
Molecular Neurobiology, 2024
Generation of a human iPSC line from a Parkinson's disease patient with a novel CHCHD2 mutation (p.R145Q).
Chen X et al.
Stem Cell Research, 2024
Aberrant CHCHD2-associated mitochondriopathy in Kii ALS/PDC astrocytes.
Leventoux N et al.
Acta Neuropathologica, 2024
Genetic and pharmacologic p32-inhibition rescue CHCHD2-linked Parkinson's disease phenotypes in vivo and in cell models.
Tio M et al.
Journal of Biomedical Science, 2024
Involvement of casein kinase 1 epsilon/delta (Csnk1e/d) in the pathogenesis of familial Parkinson's disease caused by CHCHD2.
Torii S et al.
Embo Molecular Medicine, 2023
Genetic Movement Disorders Commonly Seen in Asians.
Jagota P et al.
Movement Disorders Clinical Practice, 2023
Pathological characterization of a novel mouse model expressing the PD-linked CHCHD2-T61I mutation.
Kee TR et al.
Human Molecular Genetics, 2022
Mouse midbrain dopaminergic neurons survive loss of the PD-associated mitochondrial protein CHCHD2.
Nguyen MK et al.
Human Molecular Genetics, 2022
Monogenic Parkinson's Disease: Genotype, Phenotype, Pathophysiology, and Genetic Testing.
Jia F et al.
Genes, 2022
CHCHD2 and CHCHD10 regulate mitochondrial dynamics and integrated stress response.
Ruan Y et al.
Cell Death & Disease, 2022
CHCHD2 and CHCHD10: Future therapeutic targets in cognitive disorder and motor neuron disorder.
Jiang T et al.
Frontiers in Neuroscience, 2022
Neurodegeneration-associated mitochondrial proteins, CHCHD2 and CHCHD10-what distinguishes the two?
Ikeda A et al.
Frontiers in Cell and Developmental Biology, 2022
Mitochondrial CHCHD2: Disease-Associated Mutations, Physiological Functions, and Current Animal Models.
Kee TR et al.
Frontiers in Aging Neuroscience, 2021
Mitochondrial CHCHD2 and CHCHD10: Roles in Neurological Diseases and Therapeutic Implications.
Zhou W et al.
The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry, 2020
PD-linked CHCHD2 mutations impair CHCHD10 and MICOS complex leading to mitochondria dysfunction.
Zhou W et al.
Human Molecular Genetics, 2019
CHCHD10 is involved in the development of Parkinson's disease caused by CHCHD2 loss-of-function mutation p.T61I.
Mao C et al.
Neurobiology of Aging, 2019
Twin CHCH Proteins, CHCHD2, and CHCHD10: Key Molecules of Parkinson's Disease, Amyotrophic Lateral Sclerosis, and Frontotemporal Dementia.
Imai Y et al.
International Journal of Molecular Sciences, 2019
CHCHD2 mutational screening in Brazilian patients with familial Parkinson's disease.
Voigt DD et al.
Neurobiology of Aging, 2019
Identification of CHCHD2 mutations in patients with Alzheimer's disease, amyotrophic lateral sclerosis and frontotemporal dementia in China.
Liu X et al.
Molecular Medicine Reports, 2018
A new CHCHD2 mutation identified in a southern italy patient with multiple system atrophy.
Nicoletti G et al.
Parkinsonism & Related Disorders, 2018
Mitochondrial CHCHD-Containing Proteins: Physiologic Functions and Link with Neurodegenerative Diseases.
Zhou ZD et al.
Molecular Neurobiology, 2017
Varied pathological and therapeutic response effects associated with CHCHD2 mutant and risk variants.
Tio M et al.
Human Mutation, 2017
Pathophysiologic effects of CHCHD2 variants associated with late-onset Parkinson disease.
Kim JM
Human Mutation, 2017
Loss of Parkinson's disease-associated protein CHCHD2 affects mitochondrial crista structure and destabilizes cytochrome c.
Meng H et al.
Nature Communications, 2017
Genetic analysis of CHCHD2 in a southern Spanish population.
Tejera-Parrado C et al.
Neurobiology of Aging, 2017
Analysis of CHCHD2 gene in familial Parkinson's disease from Calabria.
Gagliardi M et al.
Neurobiology of Aging, 2017
MNRR1, a Biorganellar Regulator of Mitochondria.
Grossman LI et al.
Oxidative Medicine and Cellular Longevity, 2017
Genetic analysis of CHCHD2 gene in Chinese Parkinson's disease.
Li NN et al.
American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics, 2016
Mutational analysis of CHCHD2 in Chinese patients with multiple system atrophy and amyotrophic lateral sclerosis.
Yang X et al.
Journal of the Neurological Sciences, 2016
Mutation analysis of the CHCHD2 gene in Chinese Han patients with Parkinson's disease.
Lu Q et al.
Parkinsonism & Related Disorders, 2016
Mutational scanning of the CHCHD2 gene in Han Chinese patients with Parkinson's disease and meta-analysis of the literature.
Yang X et al.
Parkinsonism & Related Disorders, 2016
Mitochondrial Proteins Containing Coiled-Coil-Helix-Coiled-Coil-Helix (CHCH) Domains in Health and Disease.
Modjtahedi N et al.
Trends in Biochemical Sciences, 2016
Mutation analysis of CHCHD2 in Canadian patients with familial Parkinson's disease.
Zhang M et al.
Neurobiology of Aging, 2016
CHCHD2 gene mutations in familial and sporadic Parkinson's disease.
Shi CH et al.
Neurobiology of Aging, 2016
Mutation analysis of CHCHD2 gene in Chinese familial Parkinson's disease.
Liu Z et al.
Neurobiology of Aging, 2015
CHCHD2 and Parkinson's disease--authors' reply.
Funayama M et al.
The Lancet. Neurology, 2015
CHCHD2 mutations in autosomal dominant late-onset Parkinson's disease: a genome-wide linkage and sequencing study.
Funayama M et al.
The Lancet. Neurology, 2015