Varaico: Literature-Extracted Genetic Variants

Gene:CHCHD4
Variant:p.P23Q
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CHCHD4

NM_001098502.2:p.P23Q

Associated Papers

CHCHD4 confers metabolic vulnerabilities to tumour cells through its control of the mitochondrial respiratory chain.

Thomas LW et al.

Cancer & Metabolism, 2019

CHCHD4 regulates tumour proliferation and EMT-related phenotypes, through respiratory chain-mediated metabolism.

Thomas LW et al.

Cancer & Metabolism, 2019

CHCHD4 Regulates Intracellular Oxygenation and Perinuclear Distribution of Mitochondria.

Thomas LW et al.

Frontiers in Oncology, 2017

Human CHCHD4 mitochondrial proteins regulate cellular oxygen consumption rate and metabolism and provide a critical role in hypoxia signaling and tumor progression.

Yang J et al.

The Journal of Clinical Investigation, 2012

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."