Varaico: Literature-Extracted Genetic Variants

Gene:CHD1L
Variant:p.D723A
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CHD1L

NM_004284.6:p.D723A

Associated Papers

Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD.

Hewitt G et al.

Molecular Cell, 2021

ALC1 links chromatin accessibility to PARP inhibitor response in homologous recombination-deficient cells.

Verma P et al.

Nature Cell Biology, 2021

Direct measurement of protein-protein interactions by FLIM-FRET at UV laser-induced DNA damage sites in living cells.

Kaufmann T et al.

Nucleic Acids Research, 2020

Tripartite Motif-containing 33 (TRIM33) protein functions in the poly(ADP-ribose) polymerase (PARP)-dependent DNA damage response through interaction with Amplified in Liver Cancer 1 (ALC1) protein.

Kulkarni A et al.

The Journal of Biological Chemistry, 2013

CHD1L: a new candidate gene for congenital anomalies of the kidneys and urinary tract (CAKUT).

Brockschmidt A et al.

Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association, 2012

Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1.

Ahel D et al.

Science (new York, N.y.), 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."