Varaico: Literature-Extracted Genetic Variants

Gene:CHD4
Variant:p.R1162W
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CHD4

NM_001273.5:p.R1162W

Associated Papers

Epigenetic Dysregulation in Cancer: Implications for Gene Expression and DNA Repair-Associated Pathways.

Rembiałkowska N et al.

International Journal of Molecular Sciences, 2025

Chromatin Remodulator CHD4: A Potential Target for Cancer Interception.

Goswami K et al.

Genes, 2025

The theory of massively repeated evolution and full identifications of cancer-driving nucleotides (CDNs).

Zhang L et al.

Elife, 2024

39688960 (PubMed )
Supplement: elife-99340-supp1.xlsx › CDN.Missense.gnomad

Mutational landscape of cancer-driver genes across human cancers.

Sinkala M

Scientific Reports, 2023

37550388 (PubMed )
Supplement: 41598_2023_39608_MOESM6_ESM.xlsx › Sheet1

Genomic Complexity Predicts Resistance to Endocrine Therapy and CDK4/6 Inhibition in Hormone Receptor-Positive (HR+)/HER2-Negative Metastatic Breast Cancer.

Davis AA et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2023

36693175 (PubMed )
Supplement: ccr-22-2177_supplementary_data_s1_suppds1.xlsx › Variants

Clinical implications of plasma circulating tumor DNA in gynecologic cancer patients.

Charo LM et al.

Molecular Oncology, 2021

32881280 (PubMed )
Supplement: MOL2-15-67-s001.docx

Role of Chromodomain-Helicase-DNA-Binding Protein 4 (CHD4) in Breast Cancer.

Novillo A et al.

Frontiers in Oncology, 2021

SinoDuplex: An Improved Duplex Sequencing Approach to Detect Low-frequency Variants in Plasma cfDNA Samples.

Ren Y et al.

Genomics, Proteomics & Bioinformatics, 2020

32428603 (PubMed )
Supplement: mmc6.xlsx › HD701

Diversity spectrum analysis identifies mutation-specific effects of cancer driver genes.

Dong X et al.

Communications Biology, 2020

31925297 (PubMed )
Supplement: 42003_2019_736_MOESM10_ESM.xlsx › Sheet1

The Immunogenic Potential of Recurrent Cancer Drug Resistance Mutations: An In Silico Study.

Punta M et al.

Frontiers in Immunology, 2020

33133066 (PubMed )
Supplement: Table_1.xlsx › Drivers-not-HR

The Tale of CHD4 in DNA Damage Response and Chemotherapeutic Response.

Zhang J et al.

Journal of Cancer Research and Cellular Therapeutics, 2019

CHD4 mutations promote endometrial cancer stemness by activating TGF-beta signaling.

Li Y et al.

American Journal of Cancer Research, 2018

Aromatase inhibition remodels the clonal architecture of estrogen-receptor-positive breast cancers.

Miller CA et al.

Nature Communications, 2016

27502118 (PubMed )
Supplement: ncomms12498-s3.xls › Sheet1

Landscape of somatic single-nucleotide and copy-number mutations in uterine serous carcinoma.

Zhao S et al.

Proceedings of the National Academy of Sciences of the United States of America, 2013

Exome sequencing of serous endometrial tumors identifies recurrent somatic mutations in chromatin-remodeling and ubiquitin ligase complex genes.

Le Gallo M et al.

Nature Genetics, 2012

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."