Varaico: Literature-Extracted Genetic Variants

Gene:CHEK2
Variant:p.R521L
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CHEK2

NM_007194.4:p.R521L

Associated Papers

Predisposition to hematopoietic malignancies by deleterious germline CHEK2 variants.

Stubbins RJ et al.

Leukemia, 2025

40335619 (PubMed )
Supplement: 41375_2025_2635_MOESM5_ESM.xls › CHEK2_Supplemental_Table_4_v25

Molecular and In Silico Analysis of the CHEK2 Gene in Individuals with High Risk of Cancer Predisposition from Türkiye.

Ozdemir O et al.

Cancers, 2024

39594831 (PubMed )
Supplement: cancers-16-03876-s001.zip › TableS2.xlsx › CHEK2_SuppTable2__1_

BRCA-deficient metastatic prostate cancer has an adverse prognosis and distinct genomic phenotype.

Fettke H et al.

Ebiomedicine, 2023

37549632 (PubMed )
Supplement: mmc1.xlsx › ST8
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."