Varaico: Literature-Extracted Genetic Variants

Gene:CHEK2
Variant:p.T387N
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CHEK2

NM_007194.4:p.T387N

Associated Papers

Genomic Characterization of Preclinical Prostate Cancer Cell Line Models.

Beatson EL et al.

International Journal of Molecular Sciences, 2024

ENIGMA CHEK2gether Project: A Comprehensive Study Identifies Functionally Impaired CHEK2 Germline Missense Variants Associated with Increased Breast Cancer Risk.

Stolarova L et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2023

AR phosphorylation and CHK2 kinase activity regulates IR-stabilized AR-CHK2 interaction and prostate cancer survival.

Ta HQ et al.

Elife, 2020

Genomic analysis of DNA repair genes and androgen signaling in prostate cancer.

Jividen K et al.

Bmc Cancer, 2018

30305041 (PubMed )
Supplement: 12885_2018_4848_MOESM1_ESM.xlsx › Sheet1

Deleterious CHEK2 1100delC and L303X mutants identified among 38 human breast cancer cell lines.

Wasielewski M et al.

Breast Cancer Research and Treatment, 2009

Unique substitution of CHEK2 and TP53 mutations implicated in primary prostate tumors and cancer cell lines.

Zheng L et al.

Human Mutation, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."