Varaico: Literature-Extracted Genetic Variants

Gene:CHEK2
Variant:p.D368A
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CHEK2

NM_007194.4:p.D368A

Associated Papers

BCL10 regulates RNF8/RNF168-mediated ubiquitination in the DNA damage response.

Zhao H et al.

Cell Cycle (georgetown, Tex.), 2014

Centrosomal Chk2 in DNA damage responses and cell cycle progression.

Golan A et al.

Cell Cycle (georgetown, Tex.), 2010

Oxaliplatin responses in colorectal cancer cells are modulated by CHK2 kinase inhibitors.

Pires IM et al.

British Journal of Pharmacology, 2010

The Plk1 Polo box domain mediates a cell cycle and DNA damage regulated interaction with Chk2.

Tsvetkov LM et al.

Cell Cycle (georgetown, Tex.), 2005

Polo-like kinase 1 and Chk2 interact and co-localize to centrosomes and the midbody.

Tsvetkov L et al.

The Journal of Biological Chemistry, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."