Varaico: Literature-Extracted Genetic Variants

Gene:CHEK2
Variant:p.L355P
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CHEK2

NM_007194.4:p.L355P

Associated Papers

Chk2 sustains PLK1 activity in mitosis to ensure proper chromosome segregation.

Black EM et al.

Nature Communications, 2024

Chk2 sustains PLK1 activity in mitosis to ensure proper chromosome segregation.

Black EM et al.

Biorxiv : the Preprint Server for Biology, 2024

ATM kinase inhibitor AZD0156 in combination with irinotecan and 5-fluorouracil in preclinical models of colorectal cancer.

Davis SL et al.

Bmc Cancer, 2022

36309653 (PubMed )
Supplement: 12885_2022_10084_MOESM1_ESM.pdf

Deleterious CHEK2 1100delC and L303X mutants identified among 38 human breast cancer cell lines.

Wasielewski M et al.

Breast Cancer Research and Treatment, 2009

Genetic and epigenetic analysis of CHEK2 in sporadic breast, colon, and ovarian cancers.

Williams LH et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."