Varaico: Literature-Extracted Genetic Variants

Gene:CHEK2
Variant:p.D311V
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CHEK2

NM_007194.4:p.D311V

Associated Papers

A variant in the CHEK2 promoter at a methylation site relieves transcriptional repression and confers reduced risk of lung cancer.

Zhang S et al.

Carcinogenesis, 2010

Stability of checkpoint kinase 2 is regulated via phosphorylation at serine 456.

Kass EM et al.

The Journal of Biological Chemistry, 2007

Characterization of CHEK2 mutations in prostate cancer.

Wu X et al.

Human Mutation, 2006

CHK2 kinase--a busy messenger.

Bartek J et al.

Nature Reviews. Molecular Cell Biology, 2001

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."