Varaico: Literature-Extracted Genetic Variants

Gene:CHEK2
Variant:p.T68P
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CHEK2

NM_007194.4:p.T68P

Associated Papers

Dynamics of clonal hematopoiesis and cellular responses to stress-induced toxicity in autologous stem cell transplantation.

Stein CM et al.

Leukemia, 2026

41419602 (PubMed )
Supplement: 41375_2025_2823_MOESM2_ESM.xlsx › putative_variants

Comprehensive analysis of the functional impact of single nucleotide variants of human CHEK2.

McCarthy-Leo CE et al.

Plos Genetics, 2024

39146382 (PubMed )
Supplement: pgen.1011375.s008.xlsx › All_SNVs_Data

The Link between Autosomal Dominant Polycystic Kidney Disease and Chromosomal Instability: Exploring the Relationship.

Chen PL et al.

International Journal of Molecular Sciences, 2024

Suppression of the FA pathway combined with CHK1 inhibitor hypersensitize lung cancer cells to gemcitabine.

Dai CH et al.

Scientific Reports, 2017

Mitomycin C reduces abundance of replication forks but not rates of fork progression in primary and transformed human cells.

Kehrli KR et al.

Oncoscience, 2014

A small ubiquitin binding domain inhibits ubiquitin-dependent protein recruitment to DNA repair foci.

Helchowski CM et al.

Cell Cycle (georgetown, Tex.), 2013

Distinct roles of FANCO/RAD51C protein in DNA damage signaling and repair: implications for Fanconi anemia and breast cancer susceptibility.

Somyajit K et al.

The Journal of Biological Chemistry, 2012

Genetic polymorphisms and breast cancer risk: evidence from meta-analyses, pooled analyses, and genome-wide association studies.

Peng S et al.

Breast Cancer Research and Treatment, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."