Associated Papers
Short Report: The Variants in CHEK2 in Metastatic Uveal Melanoma.
Terai M et al.
Journal of Clinical Medicine, 2025
Comprehensive analysis of the functional impact of single nucleotide variants of human CHEK2.
McCarthy-Leo CE et al.
Plos Genetics, 2024
ENIGMA CHEK2gether Project: A Comprehensive Study Identifies Functionally Impaired CHEK2 Germline Missense Variants Associated with Increased Breast Cancer Risk.
Stolarova L et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2023
Genomic analyses of germline and somatic variation in high-grade serous ovarian cancer.
Adamson AW et al.
Journal of Ovarian Research, 2023
Somatic inactivation of breast cancer predisposition genes in tumors associated with pathogenic germline variants.
Lim BWX et al.
Journal of the National Cancer Institute, 2023
Occurrence of variants of unknown clinical significance in genetic testing for hereditary breast and ovarian cancer syndrome and Lynch syndrome: a literature review and analytical observational retrospective cohort study.
Adam F et al.
Bmc Medical Genomics, 2023
Atypical ATMs: Broadening the phenotypic spectrum of ATM-associated hereditary cancer.
Borja NA et al.
Frontiers in Oncology, 2023
Uncovering the Contribution of Moderate-Penetrance Susceptibility Genes to Breast Cancer by Whole-Exome Sequencing and Targeted Enrichment Sequencing of Candidate Genes in Women of European Ancestry.
Dumont M et al.
Cancers, 2022
Breast cancer risks associated with missense variants in breast cancer susceptibility genes.
Dorling L et al.
Genome Medicine, 2022
Case report: Unique FLT4 variants associated with differential response to anlotinib in angiosarcoma.
Gu Y et al.
Frontiers in Oncology, 2022
Population-based targeted sequencing of 54 candidate genes identifies PALB2 as a susceptibility gene for high-grade serous ovarian cancer.
Song H et al.
Journal of Medical Genetics, 2021
Whole Genome Sequencing Prioritizes CHEK2, EWSR1, and TIAM1 as Possible Predisposition Genes for Familial Non-Medullary Thyroid Cancer.
Srivastava A et al.
Frontiers in Endocrinology, 2021
Identification of deleterious germline CHEK2 mutations and their association with breast and ovarian cancer.
Kleiblova P et al.
International Journal of Cancer, 2019
Functional characterization of CHEK2 variants in a Saccharomyces cerevisiae system.
Delimitsou A et al.
Human Mutation, 2019
Computational analysis of high-risk SNPs in human CHK2 gene responsible for hereditary breast cancer: A functional and structural impact.
Badgujar NV et al.
Plos One, 2019
Contribution of germline mutations in cancer predisposition genes to tumor etiology in young women diagnosed with invasive breast cancer.
Rummel SK et al.
Breast Cancer Research and Treatment, 2017
Germline mutations predisposing to diffuse large B-cell lymphoma.
Leeksma OC et al.
Blood Cancer Journal, 2017
Current perspectives on CHEK2 mutations in breast cancer.
Apostolou P et al.
Breast Cancer (dove Medical Press), 2017
DNA repair genes are selectively mutated in diffuse large B cell lymphomas.
de Miranda NF et al.
The Journal of Experimental Medicine, 2013
Response to DNA damage of CHEK2 missense mutations in familial breast cancer.
Roeb W et al.
Human Molecular Genetics, 2012
The contribution of CHEK2 to the TP53-negative Li-Fraumeni phenotype.
Ruijs MW et al.
Hereditary Cancer in Clinical Practice, 2009
Identification and characterization of novel SNPs in CHEK2 in Ashkenazi Jewish men with prostate cancer.
Tischkowitz MD et al.
Cancer Letters, 2008
Genetic and functional analysis of CHEK2 (CHK2) variants in multiethnic cohorts.
Bell DW et al.
International Journal of Cancer, 2007
Germline CHEK2 mutations in Jewish Ashkenazi women at high risk for breast cancer.
Laitman Y et al.
The Israel Medical Association Journal : Imaj, 2007
Absence of CHEK2 mutations in Spanish families with hereditary breast cancer.
Bellosillo B et al.
Cancer Genetics and Cytogenetics, 2005
Increasing evidence that germline mutations in CHEK2 do not cause Li-Fraumeni syndrome.
Sodha N et al.
Human Mutation, 2002
Destabilization of CHK2 by a missense mutation associated with Li-Fraumeni Syndrome.
Lee SB et al.
Cancer Research, 2001