Varaico: Literature-Extracted Genetic Variants

Gene:CLCA1
Variant:p.E157Q
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CLCA1

NM_001285.4:p.E157Q

Associated Papers

Structural and Biophysical Analysis of the CLCA1 VWA Domain Suggests Mode of TMEM16A Engagement.

Berry KN et al.

Cell Reports, 2020

rbCLCA1 is a putative metalloprotease family member: localization and catalytic domain identification.

Lee RM et al.

Amino Acids, 2016

Self-cleavage of human CLCA1 protein by a novel internal metalloprotease domain controls calcium-activated chloride channel activation.

Yurtsever Z et al.

The Journal of Biological Chemistry, 2012

Impaired autoproteolytic cleavage of mCLCA6, a murine integral membrane protein expressed in enterocytes, leads to cleavage at the plasma membrane instead of the endoplasmic reticulum.

Bothe MK et al.

Molecules and Cells, 2012

The murine goblet cell protein mCLCA3 is a zinc-dependent metalloprotease with autoproteolytic activity.

Bothe MK et al.

Molecules and Cells, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."