Associated Papers
Adrenal histologic and genetic characteristics of primary aldosteronism in late adulthood.
Blinder AR et al.
European Journal of Endocrinology, 2026
The adrenal gland and primary aldosteronism: anatomy, steroidogenesis, regulation, and genetic insights.
Long KC et al.
Frontiers in Endocrinology, 2025
CryoEM structures of the human CLC-2 voltage-gated chloride channel reveal a ball-and-chain gating mechanism.
Xu M et al.
Elife, 2024
Adrenal Anion Channels: New Roles in Zona Glomerulosa Physiology and in the Pathophysiology of Primary Aldosteronism.
Stölting G et al.
Handbook of Experimental Pharmacology, 2024
Primary aldosteronism: molecular medicine meets public health.
Azizan EAB et al.
Nature Reviews. Nephrology, 2023
Cryo-EM structures of ClC-2 chloride channel reveal the blocking mechanism of its specific inhibitor AK-42.
Ma T et al.
Nature Communications, 2023
Update on the Genetics of Primary Aldosteronism and Aldosterone-Producing Adenomas.
Pitsava G et al.
Current Cardiology Reports, 2022
Proton-gated anion transport governs macropinosome shrinkage.
Zeziulia M et al.
Nature Cell Biology, 2022
Pathogenesis of Primary Aldosteronism: Impact on Clinical Outcome.
Santana LS et al.
Frontiers in Endocrinology, 2022
Progress on Genetic Basis of Primary Aldosteronism.
Karwacka I et al.
Biomedicines, 2021
Novel Mutations Detection with Next-Generation Sequencing and Its Association with Clinical Outcome in Unilateral Primary Aldosteronism.
Wu CH et al.
Biomedicines, 2021
Molecular Mechanisms of Functional Adrenocortical Adenoma and Carcinoma: Genetic Characterization and Intracellular Signaling Pathway.
Shimada H et al.
Biomedicines, 2021
GENETICS IN ENDOCRINOLOGY: Impact of race and sex on genetic causes of aldosterone-producing adenomas.
Nanba K et al.
European Journal of Endocrinology, 2021
Unravelling the Genetic Basis of Primary Aldosteronism.
Mourtzi N et al.
Nutrients, 2021
Approaches to Gene Mutation Analysis Using Formalin-Fixed Paraffin-Embedded Adrenal Tumor Tissue From Patients With Primary Aldosteronism.
Nanba K et al.
Frontiers in Endocrinology, 2021
Identification of Somatic Mutations in CLCN2 in Aldosterone-Producing Adenomas.
Rege J et al.
Journal of the Endocrine Society, 2020
Pathogenesis and treatment of primary aldosteronism.
Zennaro MC et al.
Nature Reviews. Endocrinology, 2020
CUL4-DDB1-CRBN E3 Ubiquitin Ligase Regulates Proteostasis of ClC-2 Chloride Channels: Implication for Aldosteronism and Leukodystrophy.
Fu SJ et al.
Cells, 2020
Elevated aldosterone and blood pressure in a mouse model of familial hyperaldosteronism with ClC-2 mutation.
Schewe J et al.
Nature Communications, 2019
Genetic causes of primary aldosteronism.
Seidel E et al.
Experimental & Molecular Medicine, 2019
CLCN2 clicks with aldosterone-producing adenomas, too!
Scholl UI
European Journal of Endocrinology, 2019
A somatic mutation in CLCN2 identified in a sporadic aldosterone-producing adenoma.
Dutta RK et al.
European Journal of Endocrinology, 2019
Pathogenesis of hypertension in a mouse model for human CLCN2 related hyperaldosteronism.
Göppner C et al.
Nature Communications, 2019
Molecular mechanisms in primary aldosteronism
De Sousa K et al.
Journal of Molecular Endocrinology, 2019
Pathogenesis of Familial Hyperaldosteronism Type II: New Concepts Involving Anion Channels.
Stowasser M et al.
Current Hypertension Reports, 2019
Inherited Forms of Primary Hyperaldosteronism: New Genes, New Phenotypes and Proposition of A New Classification.
Perez-Rivas LG et al.
Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association, 2019
Timeline of Advances in Genetics of Primary Aldosteronism.
Meyer LS et al.
Experientia Supplementum (2012), 2019
Comparative Genomics and Transcriptome Profiling in Primary Aldosteronism.
Aristizabal Prada ET et al.
International Journal of Molecular Sciences, 2018
Hypertension: CLCN2 chloride channel mutations in primary aldosteronism.
Allison SJ
Nature Reviews. Nephrology, 2018
A gain-of-function mutation in the CLCN2 chloride channel gene causes primary aldosteronism.
Fernandes-Rosa FL et al.
Nature Genetics, 2018