Associated Papers
Adrenal histologic and genetic characteristics of primary aldosteronism in late adulthood.
Blinder AR et al.
European Journal of Endocrinology, 2026
Molecular and Genetics Perspectives on Primary Adrenocortical Hyperfunction Disorders.
Kim S et al.
International Journal of Molecular Sciences, 2024
Engineering of a high-fidelity Cas12a nuclease variant capable of allele-specific editing.
Wei J et al.
Plos Biology, 2024
Adrenal Anion Channels: New Roles in Zona Glomerulosa Physiology and in the Pathophysiology of Primary Aldosteronism.
Stölting G et al.
Handbook of Experimental Pharmacology, 2024
Cryo-EM structures of ClC-2 chloride channel reveal the blocking mechanism of its specific inhibitor AK-42.
Ma T et al.
Nature Communications, 2023
Biallelic CLCN2 mutations cause retinal degeneration by impairing retinal pigment epithelium phagocytosis and chloride channel function.
Xu P et al.
Human Genetics, 2023
Pathogenesis of Primary Aldosteronism: Impact on Clinical Outcome.
Santana LS et al.
Frontiers in Endocrinology, 2022
Novel Mutations Detection with Next-Generation Sequencing and Its Association with Clinical Outcome in Unilateral Primary Aldosteronism.
Wu CH et al.
Biomedicines, 2021
Unravelling the Genetic Basis of Primary Aldosteronism.
Mourtzi N et al.
Nutrients, 2021
Identification of Somatic Mutations in CLCN2 in Aldosterone-Producing Adenomas.
Rege J et al.
Journal of the Endocrine Society, 2020
Pathogenesis and treatment of primary aldosteronism.
Zennaro MC et al.
Nature Reviews. Endocrinology, 2020
Elevated aldosterone and blood pressure in a mouse model of familial hyperaldosteronism with ClC-2 mutation.
Schewe J et al.
Nature Communications, 2019
Genetic causes of primary aldosteronism.
Seidel E et al.
Experimental & Molecular Medicine, 2019
Pathogenesis of hypertension in a mouse model for human CLCN2 related hyperaldosteronism.
Göppner C et al.
Nature Communications, 2019
Molecular mechanisms in primary aldosteronism
De Sousa K et al.
Journal of Molecular Endocrinology, 2019
Pathogenesis of Familial Hyperaldosteronism Type II: New Concepts Involving Anion Channels.
Stowasser M et al.
Current Hypertension Reports, 2019
Inherited Forms of Primary Hyperaldosteronism: New Genes, New Phenotypes and Proposition of A New Classification.
Perez-Rivas LG et al.
Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association, 2019
Comparative Genomics and Transcriptome Profiling in Primary Aldosteronism.
Aristizabal Prada ET et al.
International Journal of Molecular Sciences, 2018
CLCN2 chloride channel mutations in familial hyperaldosteronism type II.
Scholl UI et al.
Nature Genetics, 2018