Varaico: Literature-Extracted Genetic Variants

Gene:CLCN4
Variant:p.E224A
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CLCN4

NM_001830.4:p.E224A

Associated Papers

The ClC-3 Cl-/H+ antiporter becomes uncoupled at low extracellular pH.

Matsuda JJ et al.

The Journal of Biological Chemistry, 2010

Overexpression of CLC-3 in HEK293T cells yields novel currents that are pH dependent.

Matsuda JJ et al.

American Journal of Physiology. Cell Physiology, 2008

Voltage-dependent electrogenic chloride/proton exchange by endosomal CLC proteins.

Scheel O et al.

Nature, 2005

Mechanism of anionic conduction across ClC.

Cohen J et al.

Biophysical Journal, 2004

Functional characterization of recombinant human ClC-4 chloride channels in cultured mammalian cells.

Vanoye CG et al.

The Journal of Physiology, 2002

Identification of an acid-activated Cl(-) channel from human skeletal muscles.

Kawasaki M et al.

The American Journal of Physiology, 1999

Mutational analysis demonstrates that ClC-4 and ClC-5 directly mediate plasma membrane currents.

Friedrich T et al.

The Journal of Biological Chemistry, 1999

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."