Varaico: Literature-Extracted Genetic Variants

Gene:CLPP
Variant:p.D190A
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CLPP

NM_006012.4:p.D190A

Associated Papers

Cooperative Architecture of Mitochondrial Proteome Homeostasis.

Forny P et al.

Medrxiv : the Preprint Server for Health Sciences, 2026

Selective activator of human ClpP triggers cell cycle arrest to inhibit lung squamous cell carcinoma.

Zhou LL et al.

Nature Communications, 2023

Mitochondrial ATP-Dependent Proteases-Biological Function and Potential Anti-Cancer Targets.

Feng Y et al.

Cancers, 2021

Human ClpP protease, a promising therapy target for diseases of mitochondrial dysfunction.

Luo B et al.

Drug Discovery Today, 2021

Mitochondrial ClpP-Mediated Proteolysis Induces Selective Cancer Cell Lethality.

Ishizawa J et al.

Cancer Cell, 2019

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."