Varaico: Literature-Extracted Genetic Variants

Gene:CNOT7
Variant:p.D40A
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CNOT7

NM_013354.7:p.D40A

Associated Papers

Functional Proximity across an mRNA.

Hatfield BM et al.

Biochemistry, 2025

Pnrc2 promotes rapid mRNA decay and coordinately supports early development with P-body factors Ddx6 and Ddx61.

Gallagher TL et al.

Biorxiv : the Preprint Server for Biology, 2025

Deadenylation kinetics of mixed poly(A) tails at single-nucleotide resolution.

Lee YS et al.

Nature Structural & Molecular Biology, 2024

Crystal structure and functional properties of the human CCR4-CAF1 deadenylase complex.

Chen Y et al.

Nucleic Acids Research, 2021

HELZ directly interacts with CCR4-NOT and causes decay of bound mRNAs.

Hanet A et al.

Life Science Alliance, 2019

The central region of CNOT1 and CNOT9 stimulates deadenylation by the Ccr4-Not nuclease module.

Pavanello L et al.

The Biochemical Journal, 2018

Alternative splicing of CNOT7 diversifies CCR4-NOT functions.

Chapat C et al.

Nucleic Acids Research, 2017

Structural basis for inhibition of the deadenylase activity of human CNOT6L.

Zhang Q et al.

Febs Letters, 2016

Codon Usage and 3' UTR Length Determine Maternal mRNA Stability in Zebrafish.

Mishima Y et al.

Molecular Cell, 2016

A non-proteolytic role for ubiquitin in deadenylation of MHC-I mRNA by the RNA-binding E3-ligase MEX-3C.

Cano F et al.

Nature Communications, 2015

Xenopus CAF1 requires NOT1-mediated interaction with 4E-T to repress translation in vivo.

Waghray S et al.

Rna (new York, N.y.), 2015

Human Pumilio proteins recruit multiple deadenylases to efficiently repress messenger RNAs.

Van Etten J et al.

The Journal of Biological Chemistry, 2012

Not1 mediates recruitment of the deadenylase Caf1 to mRNAs targeted for degradation by tristetraprolin.

Sandler H et al.

Nucleic Acids Research, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."