Varaico: Literature-Extracted Genetic Variants

Gene:CNOT8
Variant:p.E42A
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CNOT8

NM_001301073.2:p.E42A

Associated Papers

Crystal structure and functional properties of the human CCR4-CAF1 deadenylase complex.

Chen Y et al.

Nucleic Acids Research, 2021

Human Pumilio proteins directly bind the CCR4-NOT deadenylase complex to regulate the transcriptome.

Enwerem III et al.

Rna (new York, N.y.), 2021

Xenopus CAF1 requires NOT1-mediated interaction with 4E-T to repress translation in vivo.

Waghray S et al.

Rna (new York, N.y.), 2015

Structural basis for the Nanos-mediated recruitment of the CCR4-NOT complex and translational repression.

Bhandari D et al.

Genes & Development, 2014

Human Pumilio proteins recruit multiple deadenylases to efficiently repress messenger RNAs.

Van Etten J et al.

The Journal of Biological Chemistry, 2012

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."