Varaico: Literature-Extracted Genetic Variants

Gene:CNR1
Variant:p.T210I
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CNR1

NM_016083.6:p.T210I

Associated Papers

A novel bioassay for quantification of surface Cannabinoid receptor 1 expression.

Rodríguez-Rodríguez I et al.

Scientific Reports, 2020

Molecular basis for dramatic changes in cannabinoid CB1 G protein-coupled receptor activation upon single and double point mutations.

Scott CE et al.

Protein Science : a Publication of the Protein Society, 2013

A cannabinoid receptor 1 mutation proximal to the DRY motif results in constitutive activity and reveals intramolecular interactions involved in receptor activation.

D'Antona AM et al.

Brain Research, 2006

Mutations of CB1 T210 produce active and inactive receptor forms: correlations with ligand affinity, receptor stability, and cellular localization.

D'Antona AM et al.

Biochemistry, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."