Varaico: Literature-Extracted Genetic Variants

Gene:CNR2
Variant:p.Q63R
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CNR2

NM_001841.3:p.Q63R

Associated Papers

Association of Cannabinoid CB2 Receptor Q63R Variant With Rheumatoid Arthritis in an Iranian Cohort.

Nateghi A et al.

International Journal of Genomics, 2025

Genomic and clinical characterization of pediatric lymphoepithelioma-like carcinoma.

Que Y et al.

Journal of Translational Medicine, 2024

39633439 (PubMed )
Supplement: 12967_2024_5921_MOESM7_ESM.xlsx › 11newmerge

Cannabinoid Receptor 2 Gene Polymorphism and the Risk of Developing Rheumatoid Arthritis in Lebanese Patients.

Ismail M et al.

Cannabis and Cannabinoid Research, 2024

Association Between the Endocannabinoid System-Related Gene Variants and Epilepsy.

Hosseinzadeh Anvar L et al.

Molecular Neurobiology, 2024

Genetic variants in patients with multiple arterial aneurysms.

Körfer D et al.

Langenbeck's Archives of Surgery, 2024

39382597 (PubMed )
Supplement: 423_2024_3488_MOESM2_ESM.xlsx › Supplemental_Table_2

In utero tumor development and identification of CTNNB1 mutation in a newborn case of ossifying renal tumor of infancy.

Kasai S et al.

Pediatric Blood & Cancer, 2024

38217079 (PubMed )
Supplement: supplement_1.xlsx › SNVs

Novel NARS2 variants in a patient with early-onset status epilepticus: case study and literature review.

Yang N et al.

Bmc Pediatrics, 2024

38310242 (PubMed )
Supplement: 12887_2024_4553_MOESM1_ESM.xlsx › trio.hg38.filter

Genomic and transcriptomic analysis of breast cancer identifies novel signatures associated with response to neoadjuvant chemotherapy.

Yin G et al.

Genome Medicine, 2024

38217005 (PubMed )
Supplement: 13073_2024_1286_MOESM2_ESM.xlsx › Table_S4

Bi-allelic mutation in SEC16B alters collagen trafficking and increases ER stress.

El-Gazzar A et al.

Embo Molecular Medicine, 2023

36916446 (PubMed )
Supplement: EMMM-15-e16834-s012.xlsx › WES_SEC16B_mutant

Molecular underpinnings of exceptional response in primary malignant melanoma of the esophagus to anti-PD-1 monotherapy.

Dai J et al.

Journal for Immunotherapy of Cancer, 2023

36593066 (PubMed )
Supplement: jitc-2022-005937supp007.xls › Supplemental_Table_3

ATR represents a therapeutic vulnerability in clear cell renal cell carcinoma.

Seidel P et al.

Jci Insight, 2022

36413415 (PubMed )
Supplement: jciinsight-7-156087-s060.xlsx › 786O

Functional variation (Q63R) in the cannabinoid CB2 receptor may affect the severity of COVID-19: a human study and molecular docking.

Rastegar M et al.

Archives of Virology, 2021

Whole genome mapping and identification of single nucleotide polymorphisms of four Bangladeshi individuals and their functional significance.

Khan S et al.

Bmc Research Notes, 2021

33743798 (PubMed )
Supplement: 13104_2021_5514_MOESM4_ESM.zip › Supplementary_File_1A-1.xlsx › Supplementary_File_1A-1.exonic_

Biased Coupling to β-Arrestin of Two Common Variants of the CB2 Cannabinoid Receptor.

Turu G et al.

Frontiers in Endocrinology, 2021

High throughput profiling of undifferentiated pleomorphic sarcomas identifies two main subgroups with distinct immune profile, clinical outcome and sensitivity to targeted therapies.

Toulmonde M et al.

Ebiomedicine, 2020

33254023 (PubMed )
Supplement: mmc5.xlsx › UPS_somatic_mutations_filtered

Association of cannabinoid receptor genes (CNR1 and CNR2) polymorphisms and panic disorder.

Peiró AM et al.

Anxiety, Stress, and Coping, 2020

Cannabinoid CB2 Receptor Functional Variation (Q63R) Is Associated with Multiple Sclerosis in Iranian Subjects.

Tahamtan A et al.

Journal of Molecular Neuroscience : Mn, 2020

The association of endocannabinoid receptor genes (CNR1 and CNR2) polymorphisms with depression: A meta-analysis.

Kong X et al.

Medicine, 2019

Gene-environment interaction between an endocannabinoid system genetic polymorphism and cannabis use in first episode of psychosis.

Bioque M et al.

European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology, 2019

Insights into paediatric non-alcoholic fatty liver disease from genetic variants.

Dong J et al.

Liver International : Official Journal of the International Association for the Study of the Liver, 2019

The role of GPCRs in bone diseases and dysfunctions.

Luo J et al.

Bone Research, 2019

Association of SP-B gene 9306 A/G polymorphism (rs7316) and risk of RDS.

Fatahi N et al.

The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2018

Study of cannabinoid receptor 2 Q63R gene polymorphism in Lebanese patients with rheumatoid arthritis.

Ismail M et al.

Clinical Rheumatology, 2018

In vivo evidence that the cannabinoid receptor 2-63 RR variant is associated with the acquisition and/or expansion of HIV infection.

Sagnelli C et al.

Hiv Medicine, 2018

Genetic Variant Q63R of Cannabinoid Receptor 2 Causes Differential ERK Phosphorylation in Human Immune Cells.

Wang J et al.

Genetic Testing and Molecular Biomarkers, 2018

Genome-Wide Associations Related to Hepatic Histology in Nonalcoholic Fatty Liver Disease in Hispanic Boys.

Wattacheril J et al.

The Journal of Pediatrics, 2017

Phenotypic screening of cannabinoid receptor 2 ligands shows different sensitivity to genotype.

Hillger JM et al.

Biochemical Pharmacology, 2017

Role of Cannabinoid CB2 Receptor Gene (CNR2) Polymorphism in Children with Immune Thrombocytopenic Purpura in Beni-Suef Governorate in Egypt.

Ezzat DA et al.

The Egyptian Journal of Immunology, 2017

Cannabinoid receptor 2-63 RR variant is independently associated with severe necroinflammation in HIV/HCV coinfected patients.

Sagnelli C et al.

Plos One, 2017

CB2-63 polymorphism and immune-mediated diseases associated with HCV chronic infection.

Coppola N et al.

Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2016

Cannabinoid Receptor 2 as Antiobesity Target: Inflammation, Fat Storage, and Browning Modulation.

Rossi F et al.

The Journal of Clinical Endocrinology and Metabolism, 2016

Whole genome sequencing of an ethnic Pathan (Pakhtun) from the north-west of Pakistan.

Ilyas M et al.

Bmc Genomics, 2015

25887915 (PubMed )
Supplement: 12864_2015_1290_MOESM7_ESM.xlsx › Sheet1

Association between cannabinoid receptor type 2 Q63R variant and oligo/polyarticular juvenile idiopathic arthritis.

Bellini G et al.

Scandinavian Journal of Rheumatology, 2015

The Cannabinoid Receptor 2 Q63R Variant Modulates the Relationship between Childhood Obesity and Age at Menarche.

Bellini G et al.

Plos One, 2015

No association between the functional cannabinoid receptor type 2 Q63R variants and inflammatory bowel disease in Turkish subjects.

Yonal O et al.

The Turkish Journal of Gastroenterology : the Official Journal of Turkish Society of Gastroenterology, 2014

Association between a polymorphism in cannabinoid receptor 2 and severe necroinflammation in patients with chronic hepatitis C.

Coppola N et al.

Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association, 2014

Effect of a poly(ADP-ribose) polymerase-1 inhibitor against esophageal squamous cell carcinoma cell lines.

Nasuno T et al.

Cancer Science, 2014

24219164 (PubMed )
Supplement: cas0105-0202-SD3.xlsx › TE-6

Cannabinoid receptor 2-63 QQ variant is associated with persistently normal aminotransferase serum levels in chronic hepatitis C.

Coppola N et al.

Plos One, 2014

Evidence for the involvement of cannabinoid receptors' polymorphisms in the pathophysiology of human diseases.

Vasileiou I et al.

Expert Opinion on Therapeutic Targets, 2013

Cannabinoid CB2 receptor gene (CNR2) polymorphism is associated with chronic childhood immune thrombocytopenia in Egypt.

Mahmoud Gouda H et al.

Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis, 2013

The cannabinoid receptor type 2 Q63R variant increases the risk of celiac disease: implication for a novel molecular biomarker and future therapeutic intervention.

Rossi F et al.

Pharmacological Research, 2012

Cannabinoid receptor type 2 functional variant influences liver damage in children with non-alcoholic fatty liver disease.

Rossi F et al.

Plos One, 2012

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."