Associated Papers
TAZ ( Wwtr1 ) deficiency leads to ER stress and mitochondrial dysfunction in a mouse model of Fuchs' endothelial corneal dystrophy.
Park S et al.
Biorxiv : the Preprint Server for Biology, 2026
Generation of a Mouse Model of Fuchs Endothelial Corneal Dystrophy by Knock-in of CTG Trinucleotide Repeat Expansion in the TCF4 Gene.
Oyama Y et al.
Investigative Ophthalmology & Visual Science, 2025
Genome-wide association study of Fuchs' endothelial corneal dystrophy in the German population.
Fechner J et al.
Human Genetics, 2025
From Genes to Disease: Reassessing LOXHD1 and AGBL1's Contribution to Fuchs' Dystrophy.
Tsedilina TR et al.
International Journal of Molecular Sciences, 2025
Type VIII collagen: advances in matrix biology and translational promise.
Shi H et al.
Frontiers in Bioengineering and Biotechnology, 2025
Squishy matters - Corneal mechanobiology in health and disease.
Thomasy SM et al.
Progress in Retinal and Eye Research, 2024
Fuchs endothelial corneal dystrophy: an updated review.
Altamirano F et al.
International Ophthalmology, 2024
Novel Mechanisms Guide Innovative Molecular-Based Therapeutic Strategies for Fuchs Endothelial Corneal Dystrophy.
Chan MF et al.
Cornea, 2023
RNA-Seq-based transcriptome analysis of corneal endothelial cells derived from patients with Fuchs endothelial corneal dystrophy.
Nakagawa T et al.
Scientific Reports, 2023
Mice Deficient in TAZ (Wwtr1) Demonstrate Clinical Features of Late-Onset Fuchs' Endothelial Corneal Dystrophy.
Leonard BC et al.
Investigative Ophthalmology & Visual Science, 2023
Variant Landscape of 15 Genes Involved in Corneal Dystrophies: Report of 30 Families and Comprehensive Analysis of the Literature.
Zhu D et al.
International Journal of Molecular Sciences, 2023
Systematic review of SLC4A11, ZEB1, LOXHD1, and AGBL1 variants in the development of Fuchs' endothelial corneal dystrophy.
Tsedilina TR et al.
Frontiers in Medicine, 2023
TCF4 trinucleotide repeat expansion in Swedish cases with Fuchs' endothelial corneal dystrophy.
Viberg A et al.
Acta Ophthalmologica, 2022
Descemet membrane endothelial keratoplasty in eyes with COL8A2-associated corneal dystrophy.
Dzhaber D et al.
American Journal of Ophthalmology Case Reports, 2022
Endothelial corneal dystrophy with annular stromal clefts.
Koay SY et al.
Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie, 2021
Mitochondrial Dysfunction and Mitophagy in Fuchs Endothelial Corneal Dystrophy.
Kumar V et al.
Cells, 2021
Start codon disruption with CRISPR/Cas9 prevents murine Fuchs' endothelial corneal dystrophy.
Uehara H et al.
Elife, 2021
Diseases of the corneal endothelium.
Jeang LJ et al.
Experimental Eye Research, 2021
Fuchs endothelial corneal dystrophy: The vicious cycle of Fuchs pathogenesis.
Ong Tone S et al.
Progress in Retinal and Eye Research, 2021
Molecular Mechanisms of Fuchs and Congenital Hereditary Endothelial Corneal Dystrophies.
Malhotra D et al.
Reviews of Physiology, Biochemistry and Pharmacology, 2020
Biomechanical changes to Descemet's membrane precede endothelial cell loss in an early-onset murine model of Fuchs endothelial corneal dystrophy.
Leonard BC et al.
Experimental Eye Research, 2019
REVIEW: Current understanding of the pathogenesis of Fuchs' endothelial corneal dystrophy.
Nanda GG et al.
Molecular Vision, 2019
Phenotypic Characterization of Corneal Endothelial Dystrophy in German Shorthaired and Wirehaired Pointers Using In Vivo Advanced Corneal Imaging and Histopathology.
Shull OR et al.
Cornea, 2018
Mutational spectrum of Korean patients with corneal dystrophy.
Chae H et al.
Clinical Genetics, 2016
Analysis of SLC4A11, ZEB1, LOXHD1, COL8A2 and TCF4 gene sequences in a multi-generational family with late-onset Fuchs corneal dystrophy.
Tang H et al.
International Journal of Molecular Medicine, 2016
Distinct Clinical Phenotype of Corneal Dystrophy Predicts the p.(Leu450Trp) Substitution in COL8A2.
Eghrari AO et al.
Cornea, 2016
CRISPR/Cas9 DNA cleavage at SNP-derived PAM enables both in vitro and in vivo KRT12 mutation-specific targeting.
Courtney DG et al.
Gene Therapy, 2016
Fuchs endothelial corneal dystrophy: current perspectives.
Vedana G et al.
Clinical Ophthalmology (auckland, N.z.), 2016
The pathophysiology of Fuchs' endothelial dystrophy--a review of molecular and cellular insights.
Zhang J et al.
Experimental Eye Research, 2015
Association of ZEB1 and TCF4 rs613872 changes with late onset Fuchs endothelial corneal dystrophy in patients from northern India.
Gupta R et al.
Molecular Vision, 2015
Screening of the COL8A2 gene in an Australian family with early-onset Fuchs' endothelial corneal dystrophy.
Kuot A et al.
Clinical & Experimental Ophthalmology, 2014
Genetics of the corneal endothelial dystrophies: an evidence-based review.
Aldave AJ et al.
Clinical Genetics, 2013
The genetics of Fuchs' corneal dystrophy.
Iliff BW et al.
Expert Review of Ophthalmology, 2012
Molecular bases of corneal endothelial dystrophies.
Schmedt T et al.
Experimental Eye Research, 2012
Differing roles for TCF4 and COL8A2 in central corneal thickness and fuchs endothelial corneal dystrophy.
Igo RP et al.
Plos One, 2012
A cellular model for the investigation of Fuchs' endothelial corneal dystrophy.
Kelliher C et al.
Experimental Eye Research, 2011
Replication of TCF4 through association and linkage studies in late-onset Fuchs endothelial corneal dystrophy.
Li YJ et al.
Plos One, 2011
Age-severity relationships in families linked to FCD2 with retroillumination photography.
McGlumphy EJ et al.
Investigative Ophthalmology & Visual Science, 2010
Evidence of oxidative stress in the pathogenesis of fuchs endothelial corneal dystrophy.
Jurkunas UV et al.
The American Journal of Pathology, 2010
Distribution of COL8A2 and COL8A1 gene variants in Caucasian primary open angle glaucoma patients with thin central corneal thickness.
Desronvil T et al.
Molecular Vision, 2010
Genetic analysis of patients with Fuchs endothelial corneal dystrophy in India.
Hemadevi B et al.
Bmc Ophthalmology, 2010
Progression of Fuchs corneal dystrophy in a family linked to the FCD1 locus.
Meadows DN et al.
Investigative Ophthalmology & Visual Science, 2009
Q455V mutation in COL8A2 is associated with Fuchs' corneal dystrophy in Korean patients.
Mok JW et al.
Eye (london, England), 2009
Genome-wide linkage scan in fuchs endothelial corneal dystrophy.
Afshari NA et al.
Investigative Ophthalmology & Visual Science, 2009
Essential role for the alpha 1 chain of type VIII collagen in zebrafish notochord formation.
Gansner JM et al.
Developmental Dynamics : an Official Publication of the American Association of Anatomists, 2008