Associated Papers
Corin Missense Variants, Blood Pressure, and Hypertension in 11 322 Black Individuals: Insights From REGARDS and the Jackson Heart Study.
Parcha V et al.
Journal of the American Heart Association, 2022
Associations of corin genetic polymorphisms with salt sensitivity, blood pressure changes, and hypertension incidence in Chinese adults.
Zou T et al.
Journal of Clinical Hypertension (greenwich, Conn.), 2021
Rare, Damaging DNA Variants in CORIN and Risk of Coronary Artery Disease: Insights From Functional Genomics and Large-Scale Sequencing Analyses.
Wang M et al.
Circulation. Genomic and Precision Medicine, 2021
Single-Nucleotide Polymorphisms in the 3' Untranslated Region of CORIN Associated With Cardiovascular Diseases in a Chinese Han Population: A Case-Control Study.
Zhao Y et al.
Frontiers in Cardiovascular Medicine, 2021
A common CORIN variant in hypertension reduces corin intracellular trafficking by exposing an inhibitory N-terminus.
He M et al.
Biochemical and Biophysical Research Communications, 2020
Associations between potentially functional CORIN SNPs and serum corin levels in the Chinese Han population.
Zhang H et al.
Bmc Genetics, 2019
Pregnancy-Associated Cardiac Hypertrophy in Corin-Deficient Mice: Observations in a Transgenic Model of Preeclampsia.
Baird RC et al.
The Canadian Journal of Cardiology, 2019
Association of rs2271037 and rs3749585 polymorphisms in CORIN with susceptibility to hypertension in a Chinese Han population: A case-control study.
Chen YL et al.
Gene, 2018
Functional analysis of corin protein domains required for PCSK6-mediated activation.
Chen S et al.
The International Journal of Biochemistry & Cell Biology, 2018
Identification and functional analysis of CORIN variants in hypertensive patients.
Zhang Y et al.
Human Mutation, 2017
The Uromodulin Gene Locus Shows Evidence of Pathogen Adaptation through Human Evolution.
Ghirotto S et al.
Journal of the American Society of Nephrology : Jasn, 2016
PCSK6-mediated corin activation is essential for normal blood pressure.
Chen S et al.
Nature Medicine, 2015
A corin variant identified in hypertensive patients that alters cytoplasmic tail and reduces cell surface expression and activity.
Zhang Y et al.
Scientific Reports, 2014
Corin mutations K317E and S472G from preeclamptic patients alter zymogen activation and cell surface targeting. [Corrected].
Dong N et al.
The Journal of Biological Chemistry, 2014
Blood pressure and urinary sodium excretion in relation to 16 genetic polymorphisms in the natriuretic peptide system in Chinese.
Hu BC et al.
Endocrine Journal, 2014
Highly significant association between two common single nucleotide polymorphisms in CORIN gene and preeclampsia in Caucasian women.
Stepanian A et al.
Plos One, 2014
Ankle-brachial index in relation to the natriuretic peptide system polymorphisms and urinary sodium excretion in Chinese.
Hu BC et al.
Atherosclerosis, 2013
Corin mutation R539C from hypertensive patients impairs zymogen activation and generates an inactive alternative ectodomain fragment.
Dong N et al.
The Journal of Biological Chemistry, 2013
Salt-sensitive hypertension and cardiac hypertrophy in transgenic mice expressing a corin variant identified in blacks.
Wang W et al.
Hypertension (dallas, Tex. : 1979), 2012
Exome sequencing reveals comprehensive genomic alterations across eight cancer cell lines.
Chang H et al.
Plos One, 2011
Dysfunctional corin i555(p568) allele is associated with impaired brain natriuretic peptide processing and adverse outcomes in blacks with systolic heart failure: results from the Genetic Risk Assessment in Heart Failure substudy.
Rame JE et al.
Circulation. Heart Failure, 2009
Genomics, transcriptional profiling, and heart failure.
Margulies KB et al.
Journal of the American College of Cardiology, 2009
Corin: new insights into the natriuretic peptide system.
Wu Q et al.
Kidney International, 2009
Corin variant associated with hypertension and cardiac hypertrophy exhibits impaired zymogen activation and natriuretic peptide processing activity.
Wang W et al.
Circulation Research, 2008
Corin I555(P568) allele is associated with enhanced cardiac hypertrophic response to increased systemic afterload.
Rame JE et al.
Hypertension (dallas, Tex. : 1979), 2007
Corin gene minor allele defined by 2 missense mutations is common in blacks and associated with high blood pressure and hypertension.
Dries DL et al.
Circulation, 2005