Associated Papers
The CB1 receptor interacts with cereblon and drives cereblon deficiency-associated memory shortfalls.
Costas-Insua C et al.
Embo Molecular Medicine, 2024
Cereblon-mediated degradation of the amyloid precursor protein via the ubiquitin-proteasome pathway.
Kurihara T et al.
Biochemical and Biophysical Research Communications, 2020
Cereblon attenuates DNA damage-induced apoptosis by regulating the transcription-independent function of p53.
Zhou L et al.
Cell Death & Disease, 2019
Thalidomide promotes degradation of SALL4, a transcription factor implicated in Duane Radial Ray syndrome.
Donovan KA et al.
Elife, 2018
Cereblon Maintains Synaptic and Cognitive Function by Regulating BK Channel.
Choi TY et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience, 2018
CRL4 antagonizes SCFFbxo7-mediated turnover of cereblon and BK channel to regulate learning and memory.
Song T et al.
Plos Genetics, 2018
A Comprehensive Atlas of E3 Ubiquitin Ligase Mutations in Neurological Disorders.
George AJ et al.
Frontiers in Genetics, 2018
29491882 (PubMed )
Supplement: Table2.xlsx › Sheet1
A missense mutation in the CRBN gene that segregates with intellectual disability and self-mutilating behaviour in a consanguineous Saudi family.
Sheereen A et al.
Journal of Medical Genetics, 2017
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