Varaico: Literature-Extracted Genetic Variants

Gene:CRBN
Variant:p.C366S
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CRBN

NM_016302.4:p.C366S

Associated Papers

Structural bases of IMiD selectivity that emerges by 5-hydroxythalidomide.

Furihata H et al.

Nature Communications, 2020

Positive selection of cereblon modified function including its E3 ubiquitin ligase activity and binding efficiency with AMPK.

Onodera W et al.

Molecular Phylogenetics and Evolution, 2019

Ligand-mediated protein degradation reveals functional conservation among sequence variants of the CUL4-type E3 ligase substrate receptor cereblon.

Akuffo AA et al.

The Journal of Biological Chemistry, 2018

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."