Varaico: Literature-Extracted Genetic Variants

Gene:CRBN
Variant:p.D249Y
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CRBN

NM_016302.4:p.D249Y

Associated Papers

Ubiquitin-specific proximity labeling for the identification of E3 ligase substrates.

Huang HT et al.

Nature Chemical Biology, 2024

The genetic heterogeneity and drug resistance mechanisms of relapsed refractory multiple myeloma.

Vo JN et al.

Nature Communications, 2022

CRL4 antagonizes SCFFbxo7-mediated turnover of cereblon and BK channel to regulate learning and memory.

Song T et al.

Plos Genetics, 2018

Absence of mutations in cereblon (CRBN) and DNA damage-binding protein 1 (DDB1) genes and significance for IMiD therapy.

Thakurta A et al.

Leukemia, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."