Associated Papers
Decoding the mechanisms of cooperative DNA binding by the Paired-like homeodomain family.
Cain B et al.
Biorxiv : the Preprint Server for Biology, 2025
Cone Rod Homeobox (CRX): literature review and new insights.
Leigh A et al.
Ophthalmic Genetics, 2025
Systematic review of genotype-phenotype associations in CRX-associated retinal dystrophies.
Banjak M et al.
Bmj Open Ophthalmology, 2025
Aberrant homeodomain-DNA cooperative dimerization underlies distinct developmental defects in two dominant CRX retinopathy models.
Zheng Y et al.
Genome Research, 2025
Retinal Organoids from Induced Pluripotent Stem Cells of Patients with Inherited Retinal Diseases: A Systematic Review.
Lee YJ et al.
Stem Cell Reviews and Reports, 2025
Mutational scanning of CRX classifies clinical variants and reveals biochemical properties of the transcriptional effector domain.
Shepherdson JL et al.
Genome Research, 2024
Gene Therapy for Retinitis Pigmentosa: Current Challenges and New Progress.
Liu Y et al.
Biomolecules, 2024
Mutational scanning of CRX classifies clinical variants and reveals biochemical properties of the transcriptional effector domain.
Shepherdson JL et al.
Biorxiv : the Preprint Server for Biology, 2024
Aberrant homeodomain-DNA cooperative dimerization underlies distinct developmental defects in two dominant CRX retinopathy models.
Zheng Y et al.
Biorxiv : the Preprint Server for Biology, 2024
Transcriptional precision in photoreceptor development and diseases - Lessons from 25 years of CRX research.
Zheng Y et al.
Frontiers in Cellular Neuroscience, 2024
Application of patient-derived induced pluripotent stem cells and organoids in inherited retinal diseases.
Liang Y et al.
Stem Cell Research & Therapy, 2023
Missense mutations in CRX homeodomain cause dominant retinopathies through two distinct mechanisms.
Zheng Y et al.
Elife, 2023
Missense mutations in CRX homeodomain cause dominant retinopathies through two distinct mechanisms.
Zheng Y et al.
Biorxiv : the Preprint Server for Biology, 2023
Disease-causing mutations in genes encoding transcription factors critical for photoreceptor development.
Sun C et al.
Frontiers in Molecular Neuroscience, 2023
Gene Augmentation for Autosomal Dominant CRX-Associated Retinopathies.
Sun C et al.
Advances in Experimental Medicine and Biology, 2023
Retinal Organoids: A Human Model System for Development, Diseases, and Therapies.
Kandoi S et al.
Advances in Experimental Medicine and Biology, 2023
Various phenotypes of autosomal dominant cone-rod dystrophy with cone-rod homeobox mutation in two Chinese families.
Cui H et al.
International Journal of Ophthalmology, 2022
Allele-specific gene editing to rescue dominant CRX-associated LCA7 phenotypes in a retinal organoid model.
Chirco KR et al.
Stem Cell Reports, 2021
Gene Therapy of Dominant CRX-Leber Congenital Amaurosis using Patient Stem Cell-Derived Retinal Organoids.
Kruczek K et al.
Stem Cell Reports, 2021
Clinical and Genetic Characteristics of 18 Patients from 13 Japanese Families with CRX-associated retinal disorder: Identification of Genotype-phenotype Association.
Fujinami-Yokokawa Y et al.
Scientific Reports, 2020
Pathogenicity discrimination and genetic test reference for CRX variants based on genotype-phenotype analysis.
Yi Z et al.
Experimental Eye Research, 2019
Autosomal-dominant Leber Congenital Amaurosis Caused by a Heterozygous CRX Mutation in a Father and Son.
Arcot Sadagopan K et al.
Ophthalmic Genetics, 2015
Mechanisms of blindness: animal models provide insight into distinct CRX-associated retinopathies.
Tran NM et al.
Developmental Dynamics : an Official Publication of the American Association of Anatomists, 2014
The phenotypic variability of retinal dystrophies associated with mutations in CRX, with report of a novel macular dystrophy phenotype.
Hull S et al.
Investigative Ophthalmology & Visual Science, 2014
Mechanistically distinct mouse models for CRX-associated retinopathy.
Tran NM et al.
Plos Genetics, 2014
Two novel CRX mutant proteins causing autosomal dominant Leber congenital amaurosis interact differently with NRL.
Nichols LL et al.
Human Mutation, 2010