Associated Papers
Multimeric transcription factor BCL11A utilizes two zinc-finger tandem arrays to bind clustered short sequence motifs.
Horton JR et al.
Nature Communications, 2025
Binding domain mutations provide insight into CTCF's relationship with chromatin and its contribution to gene regulation.
Do C et al.
Cell Genomics, 2025
Brain and cancer associated binding domain mutations provide insight into CTCF's relationship with chromatin and its ability to act as a chromatin organizer.
Do C et al.
Research Square, 2024
Structures of CTCF-DNA complexes including all 11 zinc fingers.
Yang J et al.
Nucleic Acids Research, 2023
Effect of Single-Residue Mutations on CTCF Binding to DNA: Insights from Molecular Dynamics Simulations.
Mao A et al.
International Journal of Molecular Sciences, 2023
Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia.
Ren R et al.
The Journal of Biological Chemistry, 2023
CTCF DNA-binding domain undergoes dynamic and selective protein-protein interactions.
Zhou R et al.
Iscience, 2022
36117989 (PubMed )
Supplement: mmc3.xlsx › Sheet1
Structure-function relationships explain CTCF zinc finger mutation phenotypes in cancer.
Bailey CG et al.
Cellular and Molecular Life Sciences : Cmls, 2021
Somatic POLE exonuclease domain mutations are early events in sporadic endometrial and colorectal carcinogenesis, determining driver mutational landscape, clonal neoantigen burden and immune response.
Temko D et al.
The Journal of Pathology, 2018
29604063 (PubMed )
Supplement: PATH-245-283-s021.xlsx › EC.Drivers.Edited
CTCF genetic alterations in endometrial carcinoma are pro-tumorigenic.
Marshall AD et al.
Oncogene, 2017
Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA.
Hashimoto H et al.
Molecular Cell, 2017
Mutational landscape and significance across 12 major cancer types.
Kandoth C et al.
Nature, 2013
24132290 (PubMed )
Supplement: 41586_2013_BFnature12634_MOESM82_ESM.zip › nature12634-s1 › Supplementary_Table_5.xlsx › S_Table_5
Exome sequencing of serous endometrial tumors identifies recurrent somatic mutations in chromatin-remodeling and ubiquitin ligase complex genes.
Le Gallo M et al.
Nature Genetics, 2012
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