Varaico: Literature-Extracted Genetic Variants

Gene:CTLA4
Variant:p.T106T
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CTLA4

NM_005214.5:p.T106T

Associated Papers

CTLA4 genetic variants influence immune regulation and susceptibility of HPV associated cervical cancer.

de Oliveira MC et al.

Discover Oncology, 2025

CTLA4 Haplotype Structures and -318 C>T (rs5742909) Genetic Variant Contribute to the Susceptibility of HPV Infection and Cervical Cancer.

de Oliveira MC et al.

Viruses, 2025

Association between CTLA4 polymorphisms and susceptibility to granulomatosis with polyangiitis.

Mohamadi A et al.

International Reviews of Immunology, 2025

The Goat Cytotoxic T Lymphocyte-Associated Antigen-4 Gene: mRNA Expression and Association Analysis of Insertion/Deletion Variants with the Risk of Brucellosis.

Wang C et al.

International Journal of Molecular Sciences, 2024

Association of four CTLA-4 gene polymorphisms with pemphigus risk: a systematic review, meta-analysis, and meta-regression.

Dhaouadi T et al.

The Journal of International Medical Research, 2024

Relationship Between Cytotoxic T-Lymphocyte-associated Antigen-4: Programmed Death-1 Genes Polymorphisms and Susceptibility to Pediatric B-Cell Acute Lymphoblastic Leukemia.

Aref S et al.

Journal of Pediatric Hematology/oncology, 2024

Association of CTLA-4 (AT)n Variants in Basal Cell Carcinoma and Squamous Cell Carcinoma Patients from Western Mexico.

Rojas-Diaz JM et al.

Current Issues in Molecular Biology, 2024

Effects of CTLA-4 Single Nucleotide Polymorphisms on Toxicity of Ipilimumab-Containing Regimens in Patients With Advanced Stage Melanoma.

de Joode K et al.

Journal of Immunotherapy (hagerstown, Md. : 1997), 2024

CTLA-4 expression and polymorphisms in Schizophrenia; a systematic review of literature.

Fayedeh F et al.

Molecular Biology Reports, 2024

Association between CTLA4 + 49A/G polymorphism and risk of hepatocellular carcinoma: a systematic review and meta-analysis.

Tan X et al.

Nucleosides, Nucleotides & Nucleic Acids, 2024

Cytotoxic T-lymphocyte associated protein 4 (CTLA4) polymorphisms are linked to systemic lupus erythematosus: an updated meta-analysis.

Suvankar S et al.

Biotechnology & Genetic Engineering Reviews, 2023

The Relationship Between CTLA-4 (-318 C/T) Polymorphism and Urothelial Cancer Carcinogenesis in Japanese Patients.

Damayanti P et al.

Cureus, 2023

The C55A Single Nucleotide Polymorphism in CTLA-4 Gene, a New Possible Biomarker in Thyroid Autoimmune Pathology Such as Hashimoto's Thyroiditis.

Chiorean AD et al.

Diagnostics (basel, Switzerland), 2023

Genetic variants and risk of endocrine autoimmunity in relatives of patients with Addison's disease.

Fichna M et al.

Endocrine Connections, 2023

Cytotoxic T-lymphocyte antigen 4 polymorphisms and breast cancer susceptibility: Evidence from a meta-analysis.

Chang HY et al.

Journal of the Chinese Medical Association : Jcma, 2023

Meta-analysis of the rs231775 locus polymorphism in the CTLA-4 gene and the susceptibility to Graves' disease in children.

Shi M et al.

Open Life Sciences, 2023

Survey of the association between polymorphisms of CTLA-4 exon 1 49 A/G genes with rheumatoid arthritis in Iran.

Lashgari M et al.

Journal of Immunoassay & Immunochemistry, 2022

Polymorphisms in CTLA-4 predict de novo donor specific antibody formation after kidney transplantation.

Ono K et al.

Human Immunology, 2022

Influence of cytotoxic T lymphocyte antigen 4 genetic variants on acute rejection in kidney transplant patients: precision medicine perspective.

Taleb A et al.

Journal of Diabetes and Metabolic Disorders, 2022

Meta-Analysis of the Genetic Association between PTPN22 and CTLA-4 Variants and Risk of Uveitis.

Zhang J et al.

Ophthalmic Research, 2022

CTLA-4 CT-60 A/G and CTLA-4 1822 C/T Gene Polymorphisms in Indonesians with Type 1 Diabetes Mellitus.

Rochmah N et al.

The Application of Clinical Genetics, 2022

Functional Impact of Risk Gene Variants on the Autoimmune Responses in Type 1 Diabetes.

Gootjes C et al.

Frontiers in Immunology, 2022

Association of CLTA-4 Gene Polymorphisms with Diabetes Mellitus: A Study Based on the Han Population of Northern China.

Ren D et al.

Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy, 2022

HLA and Non-HLA gene polymorphisms in autoimmune hepatitis patients of North Indian adults.

Ahuja N et al.

Frontiers in Immunology, 2022

Lupus susceptibility region containing CTLA4 rs17268364 functionally reduces CTLA4 expression by binding EWSR1 and correlates IFN-α signature.

Qi YY et al.

Arthritis Research & Therapy, 2021

Association between CTLA-4 gene polymorphism and risk of rheumatoid arthritis: a meta-analysis.

Zhou C et al.

Aging, 2021

Genetic Polymorphisms of Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4) and clinical outcomes post-allogeneic hematopoietic stem cell transplantation: A systematic review and meta-analysis.

Najafi A et al.

Clinical Transplantation, 2021

Investigation of the relationship between CTLA4 and the tumor suppressor RASSF1A and the possible mediating role of STAT4 in a cohort of Egyptian patients infected with hepatitis C virus with and without hepatocellular carcinoma.

Ali NA et al.

Archives of Virology, 2021

FOXP3 and CTLA-4 genetic variants' influence on the susceptibility and clinical course of basal cell carcinoma.

Sławińska M et al.

Postepy Dermatologii I Alergologii, 2021

CTLA-4 +49 A/G Polymorphism and the Risk of Lung Cancer: a Meta-analysis.

Wei Z et al.

Zhongguo Fei Ai Za Zhi = Chinese Journal of Lung Cancer, 2021

The Role of CTLA4 and Its Polymorphisms in Solid Organ and Haematopoietic Stem Cell Transplantation.

Rosik J et al.

International Journal of Molecular Sciences, 2021

Polymorphisms of the genes CTLA4, PTPN22, CD40, and PPARG and their roles in Graves' disease: susceptibility and clinical features.

Bufalo NE et al.

Endocrine, 2021

Association of the genetic polymorphisms in inhibiting and activating molecules of immune system with rheumatoid arthritis: A systematic review and meta-analysis.

Mousavi MJ et al.

Journal of Research in Medical Sciences : the Official Journal of Isfahan University of Medical Sciences, 2021

Genetic association study of CTLA4 and FCεRIα polymorphisms in asthmatic patients in the southwestern region of Iran.

Roshanizadeh Z et al.

Nucleosides, Nucleotides & Nucleic Acids, 2021

Genetic Variation of Costimulatory Molecules, Including Cytotoxic T-Lymphocyte Antigen 4, Inducible T-Cell Costimulator, Cluster Differentiation 28, and Programmed Cell Death 1 Genes, in Iranian Patients With Leukemia.

Ramzi M et al.

Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation, 2020

Distinct HLA and non-HLA associations in different subtypes of ANCA-associated vasculitides in North India.

Singh J et al.

International Journal of Rheumatic Diseases, 2020

Association of cytotoxic T-lymphocyte associated protein 4 gene polymorphisms with the risk and prognosis of oesophageal cancer in a high-incidence region from northern China.

Wang L et al.

International Journal of Immunogenetics, 2020

Uveitis genetics.

Hou S et al.

Experimental Eye Research, 2020

A significant association of the CTLA4 gene variants with the risk of autoimmune Graves' disease in ethnic Kashmiri population.

Shehjar F et al.

Cellular Immunology, 2020

Single Nucleotide Variants Associated with Colorectal Cancer Among Iranian Patients: A Narrative Review.

Jamshidi M et al.

Pharmacogenomics and Personalized Medicine, 2020

Beyond the HLA polymorphism: A complex pattern of genetic susceptibility to pemphigus.

Petzl-Erler ML

Genetics and Molecular Biology, 2020

A sequencing study of CTLA4 in Pakistani rheumatoid arthritis cases.

Aslam MM et al.

Plos One, 2020

Polymorphism in the Promoter Region of the IL18 Gene and the Association With Severity on Paracoccidioidomycosis.

Sato PK et al.

Frontiers in Immunology, 2020

Umbilical cord blood transplantation and the impact of the CTLA4 genotype on outcomes.

Szostak B et al.

Expert Review of Hematology, 2019

Polymorphisms in the cytotoxic T lymphocyte-associated protein-4 immune regulatory gene and their impact on inhibitor development in patients with hemophilia A.

Abdulqader AMR et al.

The Journal of International Medical Research, 2019

Association of CTLA-4 and CD28 Gene Polymorphisms with Type 1 Diabetes in South Indian Population.

Gunavathy N et al.

Immunological Investigations, 2019

Inflammatory and immune response genes: A genetic analysis of inhibitor development in Iranian hemophilia A patients.

Naderi N et al.

Pediatric Hematology and Oncology, 2019

Cytotoxic T- Lymphocyte Antigen-4 (CTLA4) Gene Expression and Urinary CTLA4 Levels in Idiopathic Nephrotic Syndrome.

Mishra OP et al.

Indian Journal of Pediatrics, 2019

What did we learn from CTLA-4 insufficiency on the human immune system?

Mitsuiki N et al.

Immunological Reviews, 2019

Risk stratification integrating genetic data for factor VIII inhibitor development in patients with severe hemophilia A.

Bachelet D et al.

Plos One, 2019

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."