Varaico: Literature-Extracted Genetic Variants

Gene:CTNNB1
Variant:p.K49R
Back to variants list

CTNNB1

NM_001904.4:p.K49R

Associated Papers

TRIM36 suppresses cell growth and promotes apoptosis in human esophageal squamous cell carcinoma cells by inhibiting Wnt/β-catenin signaling pathway.

Zhao B et al.

Human Cell, 2022

Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Hescheler DA et al.

Frontiers in Endocrinology, 2021

34630336 (PubMed )
Supplement: Table_1.xlsx › Tab2

Tau acetylates and stabilizes β-catenin thereby promoting cell survival.

Liu E et al.

Embo Reports, 2020

Ube2s stabilizes β-Catenin through K11-linked polyubiquitination to promote mesendoderm specification and colorectal cancer development.

Li Z et al.

Cell Death & Disease, 2018

The diagnostic application of RNA sequencing in patients with thyroid cancer: an analysis of 851 variants and 133 fusions in 524 genes.

Pagan M et al.

Bmc Bioinformatics, 2016

26818556 (PubMed )
Supplement: 12859_2015_849_MOESM3_ESM.pdf

Tubulin polymerization promoting protein 1 (TPPP1) increases β-catenin expression through inhibition of HDAC6 activity in U2OS osteosarcoma cells.

Schofield AV et al.

Biochemical and Biophysical Research Communications, 2013

FANCL ubiquitinates β-catenin and enhances its nuclear function.

Dao KH et al.

Blood, 2012

Predicting the functional impact of protein mutations: application to cancer genomics.

Reva B et al.

Nucleic Acids Research, 2011

21727090 (PubMed )
Supplement: supp_gkr407_Supplement2_Table_SM1_COSMIC_mutations.xls › Sheet1

beta-catenin is a target for the ubiquitin-proteasome pathway.

Aberle H et al.

The Embo Journal, 1997

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."