Varaico: Literature-Extracted Genetic Variants

Gene:CTNNB1
Variant:p.Q61L
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CTNNB1

NM_001904.4:p.Q61L

Associated Papers

The metastasis-promoting P1597L mutation in PlexinB1 enhances Ras activity.

Garg R et al.

Bmc Cancer, 2024

39138404 (PubMed )
Supplement: 12885_2024_12762_MOESM3_ESM.pdf

The Mutational Landscape of Cancer's Vulnerability to Ionizing Radiation.

Gopal P et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2022

Clinical Significance of Somatic Mutations in RAS/RAF/MAPK Signaling Pathway in Moroccan and North African Colorectal Cancer Patients.

Benmokhtar S et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2022

Genetic and Methylation Analysis of CTNNB1 in Benign and Malignant Melanocytic Lesions.

Zaremba A et al.

Cancers, 2022

Recurrent PTPN14 Mutations in Trichilemmoma: Evidence for Distinct Pathways of Molecular Pathogenesis.

Russell-Goldman E et al.

The American Journal of Dermatopathology, 2022

Intrinsic activation of β-catenin signaling by CRISPR/Cas9-mediated exon skipping contributes to immune evasion in hepatocellular carcinoma.

Akasu M et al.

Scientific Reports, 2021

KRAS G12C mutations in Asia: a landscape analysis of 11,951 Chinese tumor samples.

Loong HH et al.

Translational Lung Cancer Research, 2020

Whole-genome landscape of mucosal melanoma reveals diverse drivers and therapeutic targets.

Newell F et al.

Nature Communications, 2019

Expression profiling and microRNA regulation of the LKB1 pathway in young and aged lung adenocarcinoma patients.

Boldrini L et al.

Biomedical Reports, 2018

Genomic sequencing identifies a few mutations driving the independent origin of primary liver tumors in a chronic hepatitis murine model.

Yang Z et al.

Plos One, 2017

Performance of amplicon-based next generation DNA sequencing for diagnostic gene mutation profiling in oncopathology.

Sie D et al.

Cellular Oncology (dordrecht, Netherlands), 2014

Conjunctival melanomas harbor BRAF and NRAS mutations and copy number changes similar to cutaneous and mucosal melanomas.

Griewank KG et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2013

The proto-oncogene KRAS and BRAF profiles and some clinical characteristics in colorectal cancer in the Turkish population.

Ozen F et al.

Genetic Testing and Molecular Biomarkers, 2013

Evidence of a low prevalence of RAS mutations in a large medullary thyroid cancer series.

Ciampi R et al.

Thyroid : Official Journal of the American Thyroid Association, 2013

Ras mutation cooperates with β-catenin activation to drive bladder tumourigenesis.

Ahmad I et al.

Cell Death & Disease, 2011

Pharmacodynamic characterization of the efficacy signals due to selective BRAF inhibition with PLX4032 in malignant melanoma.

Tap WD et al.

Neoplasia (new York, N.y.), 2010

Menin interacts with IQGAP1 to enhance intercellular adhesion of beta-cells.

Yan J et al.

Oncogene, 2009

The transcriptional coactivator CBP interacts with beta-catenin to activate gene expression.

Takemaru KI et al.

The Journal of Cell Biology, 2000

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."