Varaico: Literature-Extracted Genetic Variants

Gene:CTNNB1
Variant:p.Y142F
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CTNNB1

NM_001904.4:p.Y142F

Associated Papers

Janus kinase 3 regulates adherens junctions and epithelial mesenchymal transition through β-catenin.

Mishra J et al.

The Journal of Biological Chemistry, 2017

Terminal regions of β-catenin are critical for regulating its adhesion and transcription functions.

Dar MS et al.

Biochimica Et Biophysica Acta, 2016

Nuclear phosphorylated Y142 β-catenin accumulates in astrocytomas and glioblastomas and regulates cell invasion.

Náger M et al.

Cell Cycle (georgetown, Tex.), 2015

SHP-1 inhibits β-catenin function by inducing its degradation and interfering with its association with TATA-binding protein.

Simoneau M et al.

Cellular Signalling, 2011

Epidermal growth factor receptor/beta-catenin/T-cell factor 4/matrix metalloproteinase 1: a new pathway for regulating keratinocyte invasiveness after UVA irradiation.

Jean C et al.

Cancer Research, 2009

A novel RET kinase-beta-catenin signaling pathway contributes to tumorigenesis in thyroid carcinoma.

Gujral TS et al.

Cancer Research, 2008

Compromised E-cadherin adhesion and epithelial barrier function with activation of G protein-coupled receptors is rescued by Y-to-F mutations in beta-catenin.

Winter MC et al.

American Journal of Physiology. Lung Cellular and Molecular Physiology, 2008

Defining the function of beta-catenin tyrosine phosphorylation in cadherin-mediated cell-cell adhesion.

Tominaga J et al.

Genes to Cells : Devoted to Molecular & Cellular Mechanisms, 2008

Cables links Robo-bound Abl kinase to N-cadherin-bound beta-catenin to mediate Slit-induced modulation of adhesion and transcription.

Rhee J et al.

Nature Cell Biology, 2007

Bcr-Abl stabilizes beta-catenin in chronic myeloid leukemia through its tyrosine phosphorylation.

Coluccia AM et al.

The Embo Journal, 2007

Continuous association of cadherin with beta-catenin requires the non-receptor tyrosine-kinase Fer.

Xu G et al.

Journal of Cell Science, 2004

Hepatocyte Growth Factor Modulates MET Receptor Tyrosine Kinase and β-Catenin Functional Interactions to Enhance Synapse Formation.

Xie Z et al.

Eneuro, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."