Varaico: Literature-Extracted Genetic Variants

Gene:CTNNB1
Variant:p.K345R
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CTNNB1

NM_001904.4:p.K345R

Associated Papers

Mutational scanning reveals substrate-assisted autoregulation of the WNT destruction complex.

Padmanarayana M et al.

Biorxiv : the Preprint Server for Biology, 2025

41278994 (PubMed )
Supplement: media-1.xlsx › WNT_DC_ABE_Screen

Neddylation is essential for β-catenin degradation in Wnt signaling pathway.

Wang B et al.

Cell Reports, 2022

β-catenin deacetylation is essential for WNT-induced proliferation of breast cancer cells.

Wang SH et al.

Molecular Medicine Reports, 2014

Glucose-induced β-catenin acetylation enhances Wnt signaling in cancer.

Chocarro-Calvo A et al.

Molecular Cell, 2013

Lysine 394 is a novel Rad6B-induced ubiquitination site on beta-catenin.

Gerard B et al.

Biochimica Et Biophysica Acta, 2012

Wilms tumour histology is determined by distinct types of precursor lesions and not epigenetic changes.

Fukuzawa R et al.

The Journal of Pathology, 2008

Acetylation of beta-catenin by p300 regulates beta-catenin-Tcf4 interaction.

Lévy L et al.

Molecular and Cellular Biology, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."