Varaico: Literature-Extracted Genetic Variants

Gene:CTRC
Variant:p.G61R
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CTRC

NM_007272.3:p.G61R

Associated Papers

Novel chymotrypsin C (CTRC) variants from real-world genetic testing of pediatric chronic pancreatitis cases.

Stefanovics R et al.

Pancreatology : Official Journal of the International Association of Pancreatology (iap) ... [et Al.], 2024

Clinical interpretation of SPINK1 and CTRC variants in pancreatitis.

Girodon E et al.

Pancreatology : Official Journal of the International Association of Pancreatology (iap) ... [et Al.], 2020

SPINK1, PRSS1, CTRC, and CFTR Genotypes Influence Disease Onset and Clinical Outcomes in Chronic Pancreatitis.

Zou WB et al.

Clinical and Translational Gastroenterology, 2018

Genetic risk in chronic pancreatitis: the misfolding-dependent pathway.

Sahin-Tóth M

Current Opinion in Gastroenterology, 2017

ER stress-associated CTRC mutants decrease stimulated pancreatic zymogen secretion through SIRT2-mediated microtubule dysregulation.

Binker MG et al.

Biochemical and Biophysical Research Communications, 2015

Comprehensive functional analysis of chymotrypsin C (CTRC) variants reveals distinct loss-of-function mechanisms associated with pancreatitis risk.

Beer S et al.

Gut, 2013

Chymotrypsin C mutations in chronic pancreatitis.

Zhou J et al.

Journal of Gastroenterology and Hepatology, 2011

Tropical calcific pancreatitis and its association with CTRC and SPINK1 (p.N34S) variants.

Derikx MH et al.

European Journal of Gastroenterology & Hepatology, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."