Associated Papers
Structure of CRL7FBXW8 reveals coupling with CUL1-RBX1/ROC1 for multi-cullin-RING E3-catalyzed ubiquitin ligation.
Hopf LVM et al.
Nature Structural & Molecular Biology, 2022
NEDD8 nucleates a multivalent cullin-RING-UBE2D ubiquitin ligation assembly.
Baek K et al.
Nature, 2020
Robust cullin-RING ligase function is established by a multiplicity of poly-ubiquitylation pathways.
Hill S et al.
Elife, 2019
AMPK-SKP2-CARM1 signalling cascade in transcriptional regulation of autophagy.
Shin HJ et al.
Nature, 2016
Substrate binding promotes formation of the Skp1-Cul1-Fbxl3 (SCF(Fbxl3)) protein complex.
Yumimoto K et al.
The Journal of Biological Chemistry, 2013
Jun activation domain-binding protein 1 (JAB1) is required for the optimal response to interferons.
Muromoto R et al.
The Journal of Biological Chemistry, 2013
NEDD8 links cullin-RING ubiquitin ligase function to the p97 pathway.
den Besten W et al.
Nature Structural & Molecular Biology, 2012
Autoinhibitory regulation of SCF-mediated ubiquitination by human cullin 1's C-terminal tail.
Yamoah K et al.
Proceedings of the National Academy of Sciences of the United States of America, 2008
Role of the NEDD8 modification of Cul2 in the sequential activation of ECV complex.
Sufan RI et al.
Neoplasia (new York, N.y.), 2006
The Nedd8-conjugated ROC1-CUL1 core ubiquitin ligase utilizes Nedd8 charged surface residues for efficient polyubiquitin chain assembly catalyzed by Cdc34.
Wu K et al.
The Journal of Biological Chemistry, 2002
Conjugation of Nedd8 to CUL1 enhances the ability of the ROC1-CUL1 complex to promote ubiquitin polymerization.
Wu K et al.
The Journal of Biological Chemistry, 2000
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