Varaico: Literature-Extracted Genetic Variants

Gene:CXCR4
Variant:p.S338fs
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CXCR4

NM_003467.3:p.S338fs

Associated Papers

Impact of chromosomal aberrations detected by chromosome banding analysis in symptomatic Waldenström's macroglobulinemia.

Ito K et al.

Annals of Hematology, 2025

Bone marrow involvement and subclonal diversity impairs detection of mutated CXCR4 by diagnostic next-generation sequencing in Waldenström macroglobulinaemia.

Gustine JN et al.

British Journal of Haematology, 2021

Aberrant CXCR4 Signaling at Crossroad of WHIM Syndrome and Waldenstrom's Macroglobulinemia.

Milanesi S et al.

International Journal of Molecular Sciences, 2020

Genomic evolution of ibrutinib-resistant clones in Waldenström macroglobulinaemia.

Jiménez C et al.

British Journal of Haematology, 2020

High-throughput sequencing of nodal marginal zone lymphomas identifies recurrent BRAF mutations.

Pillonel V et al.

Leukemia, 2018

29556019 (PubMed )
Supplement: 41375_2018_82_MOESM10_ESM.xlsx › .

Acquired mutations associated with ibrutinib resistance in Waldenström macroglobulinemia.

Xu L et al.

Blood, 2017

Clinical Validation of a CXCR4 Mutation Screening Assay for Waldenstrom Macroglobulinemia.

Ballester LY et al.

Clinical Lymphoma, Myeloma & Leukemia, 2016

Genomic Landscape of CXCR4 Mutations in Waldenström Macroglobulinemia.

Poulain S et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2016

Clonal architecture of CXCR4 WHIM-like mutations in Waldenström Macroglobulinaemia.

Xu L et al.

British Journal of Haematology, 2016

MYD88 L265P and CXCR4 mutations in lymphoplasmacytic lymphoma identify cases with high disease activity.

Schmidt J et al.

British Journal of Haematology, 2015

The WHIM-like CXCR4(S338X) somatic mutation activates AKT and ERK, and promotes resistance to ibrutinib and other agents used in the treatment of Waldenstrom's Macroglobulinemia.

Cao Y et al.

Leukemia, 2015

Somatic mutations in MYD88 and CXCR4 are determinants of clinical presentation and overall survival in Waldenstrom macroglobulinemia.

Treon SP et al.

Blood, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."