Varaico: Literature-Extracted Genetic Variants

Gene:CXCR4
Variant:p.C274S
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CXCR4

NM_003467.3:p.C274S

Associated Papers

Encoding and decoding selectivity and promiscuity in the human chemokine-GPCR interaction network.

Kleist AB et al.

Cell, 2025

Mutational analysis of the extracellular disulphide bridges of the atypical chemokine receptor ACKR3/CXCR7 uncovers multiple binding and activation modes for its chemokine and endogenous non-chemokine agonists.

Szpakowska M et al.

Biochemical Pharmacology, 2018

Third extracellular loop (EC3)-N terminus interaction is important for seven-transmembrane domain receptor function: implications for an activation microswitch region.

Rana S et al.

The Journal of Biological Chemistry, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."