Associated Papers
Encoding and decoding selectivity and promiscuity in the human chemokine-GPCR interaction network.
Kleist AB et al.
Cell, 2025
Cryo-EM structure of monomeric CXCL12-bound CXCR4 in the active state.
Liu Y et al.
Cell Reports, 2024
Functional anatomy of the full-length CXCR4-CXCL12 complex systematically dissected by quantitative model-guided mutagenesis.
Stephens BS et al.
Science Signaling, 2020
Distinct functional sites for human immunodeficiency virus type 1 and stromal cell-derived factor 1alpha on CXCR4 transmembrane helical domains.
Tian S et al.
Journal of Virology, 2005
Identification of residues of CXCR4 critical for human immunodeficiency virus coreceptor and chemokine receptor activities.
Brelot A et al.
The Journal of Biological Chemistry, 2000
Mutagenesis of CXCR4 identifies important domains for human immunodeficiency virus type 1 X4 isolate envelope-mediated membrane fusion and virus entry and reveals cryptic coreceptor activity for R5 isolates.
Chabot DJ et al.
Journal of Virology, 1999
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