Varaico: Literature-Extracted Genetic Variants

Gene:CXCR4
Variant:p.D182A
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CXCR4

NM_003467.3:p.D182A

Associated Papers

Functional anatomy of the full-length CXCR4-CXCL12 complex systematically dissected by quantitative model-guided mutagenesis.

Stephens BS et al.

Science Signaling, 2020

Distinct functional sites for human immunodeficiency virus type 1 and stromal cell-derived factor 1alpha on CXCR4 transmembrane helical domains.

Tian S et al.

Journal of Virology, 2005

Identification of residues of CXCR4 critical for human immunodeficiency virus coreceptor and chemokine receptor activities.

Brelot A et al.

The Journal of Biological Chemistry, 2000

Mutagenesis of CXCR4 identifies important domains for human immunodeficiency virus type 1 X4 isolate envelope-mediated membrane fusion and virus entry and reveals cryptic coreceptor activity for R5 isolates.

Chabot DJ et al.

Journal of Virology, 1999

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."