Varaico: Literature-Extracted Genetic Variants

Gene:CXCR4
Variant:p.Q66R
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CXCR4

NM_003467.3:p.Q66R

Associated Papers

Resistance of human immunodeficiency virus type 1 to a third-generation fusion inhibitor requires multiple mutations in gp41 and is accompanied by a dramatic loss of gp41 function.

Eggink D et al.

Journal of Virology, 2011

Genotypic analysis of the gp41 HR1 region from HIV-1 isolates from enfuvirtide-treated and untreated patients.

Pessoa LS et al.

Journal of Acquired Immune Deficiency Syndromes (1999), 2011

HR-2 mutations in human immunodeficiency virus type 1 gp41 restore fusion kinetics delayed by HR-1 mutations that cause clinical resistance to enfuvirtide.

Ray N et al.

Journal of Virology, 2009

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